TOPLINE: Prenatal exposure to triptans, alone or with other migraine medications, was not associated with a significantly increased risk for neurodevelopmental disorders (NDDs) in children born to mothers with a history of migraine in a new study. METHODOLOGY: Researchers conducted a registry-based cohort study in Norway, using data from multiple national health registries between 2008 … Read more
Novel non-Stimulant Shows Promise for Adult ADHD: Centanafadine Demonstrates Clinically Meaningful Enhancement Table of Contents Novel non-Stimulant Shows Promise for Adult ADHD: Centanafadine Demonstrates Clinically Meaningful Enhancement Centanafadine Shows Promise in ADHD Treatment: A New Approach to Symptom Management Understanding Centanafadine’s Impact on ADHD Symptoms Expanding the Research: Pediatric Trials Yield Positive Results safety Profile … Read more
LOS ANGELES — The novel norepinephrine, dopamine, and serotonin reuptake inhibitor (NDSRI) centanafadine (Otsuka Pharmaceutical Co., Ltd.) is effective and “clinically meaningful” for adult attention-deficit/hyperactivity disorder (ADHD), new research suggested. In a combined analysis of two phase 3 trials with a total of 859 adults, more patients who received the NDSRI had at least an … Read more
TOPLINE: Parental metabolic syndrome (MetS) had a notable impact on the metabolic health of offspring; paternal MetS showed stronger associations with several metabolic markers in boys, whereas maternal MetS was linked to elevated triglyceride levels in both sexes but affected other markers, primarily in boys. METHODOLOGY: Multiple studies have examined the influence of parental MetS … Read more
The Child and Youth Maltreatment Section of the Canadian Paediatric Society (CPS) has released a new Practice Point for the assessment of children with suspected traumatic head injury related to child maltreatment (THI-CM). This type of injury “is not rare and frequently results in significant morbidity for the child and family,” the CPS told Medscape … Read more
ORLANDO, Fla. — A program at Duke University School of Nursing, Durham, North Carolina, is currently one of just two in the United States that trains nurse practitioners (NPs) to provide endocrine specialty care, but more could be on the way. Established in 2016, the program was “a result of national demand for diabetes and … Read more
Proposed budget changes threaten Public Service Loan Forgiveness (PSLF) eligibility for doctors, possibly excluding residency years. This critical shift could dramatically impact medical school debt, a primary worry for many physicians. The Department of Education is also examining limits on hospital eligibility for PSLF,raising concerns about healthcare access,particularly in underserved areas. Critics say discouraging doctors … Read more
TOPLINE: Premature infants exposed to multiple courses of antibiotics around the time of birth had weaker lung function and a higher risk for asthma episodes by early school age than those with lower exposure. METHODOLOGY: The study analyzed 3820 premature infants born between 22 and 36 weeks of gestation with low birth weights (< 1500 … Read more
TOPLINE: Neonates born preterm with very low birth weight (VLBW) exposed to multiple perinatal antibiotics were at an increased risk for impaired lung function and asthma episodes at early school age, according to a new study. METHODOLOGY: This population-based, multicentre cohort analysis included 3820 neonates born preterm with VLBW (< 1500 g; median gestational age, … Read more
Editor’s Note:The Case Challenge series includes difficult-to-diagnose conditions, some of which are not frequently encountered by most clinicians, but are nonetheless important to accurately recognize. Test your diagnostic and treatment skills using the following patient scenario and corresponding questions. If you have a case that you would like to suggest for a future Case Challenge, … Read more