Age-related sperm changes at imprint regions linked to autism risk

A new research paper was published in Volume 17, Issue 12 of Aging-US on December 29, 2025, titled “Age-specific DNA methylation alterations in sperm at imprint control regions may contribute to the risk of autism spectrum disorder in offspring.” The study – selected as our Editors’ Choice for January, 2026 – was led by first authors Eugenia Casella and Jana … Read more

New clinical practice guideline advances surgical care for chronic rhinosinusitis

The American Academy of Otolaryngology–Head and Neck Surgery Foundation (AAO-HNSF) published the new Clinical Practice Guideline (CPG): Surgical Management of Chronic Rhinosinusitis today in Otolaryngology–Head and Neck Surgery. Chronic rhinosinusitis (CRS) affects 11.6% of adults and prompts 4.1 million annual ambulatory visits. Chronic rhinosinusitis doesn’t just affect the nose-it can influence a person’s general … Read more

AI approach reveals possible fusion of rare diseases in COVID-19 origins In A Landmark Dis…

Despite extensive research, the origins of COVID-19 remain elusive. In a new study published in the KeAi journal Advances in Biomarker Sciences and Technology (ABST), an AI-driven approach was adopted to examine DNA methylation patterns at 865,859 CpG sites in blood samples from early COVID-19 patients. The study was conducted by Zhengjun Zhang from the … Read more

Adenosine Deaminase 2 Regulates Toll-Like Receptor 9 Activation by Nucleic Acids

Immune System Regulator Uncovered: ADA2’s ⁤Surprising Role ​in Fighting Infections New research reveals a previously unknown ‍function for the enzyme adenosine deaminase 2​ (ADA2), highlighting its crucial role in regulating the body’s ‍immune response to infections. Scientists have long known ADA2 for its ability to break​ down ​adenosine,a molecule involved in various bodily functions. However,a … Read more