Intracellular

“Bugs Delivering Drugs” – Researchers Publish New Approach To Colorectal Cancer Treatment Using Common Food-Borne Bacteria

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Baylor University researchers have published a novel approach to fight colorectal cancer, using modified bacteria as a courier to deliver potent cancer-killing proteins into tumor cells. Michael S. VanNieuwenhze, PhD, FRSC, University Distinguished Professor and chair of the Department of Biology, along with Baylor doctoral students and a colleague at Texas Tech University Health Sciences … Read more

Researchers show red blood cells drive better glucose tolerance at high altitude

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New research reveals how hypoxia-driven red blood cell adaptations may reshape glucose regulation, offering fresh insight into diabetes biology and potential therapeutic strategies. Study: Red blood cells serve as a primary glucose sink to improve glucose tolerance at altitude. Image Credit: nobeastsofierce / Shutterstock In a recent study published in the journal Cell Metabolism, researchers investigated … Read more

Engineered Listeria boosts innate immunity against cancer

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After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system to cause listeriosis, Daniel Portnoy and his colleagues have discovered a way to turn the bacteria into a potent booster of the immune system – and a potential weapon against cancer. Three years ago, Portnoy cofounded a … Read more

New rifamycin drugs fight antibiotic-resistant lung infections more effectively

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Modified antibiotics beat a stubborn lung pathogen and dodge metabolic landmines, offering new hope for patients with HIV, cystic fibrosis, and TB co-infections. Study: Next-generation rifamycins for the treatment of mycobacterial infections. Image Credit: Kateryna Kon / Shutterstock The rise of drug-resistant bacteria is a major health crisis. Moreover, the development of antibiotic resistance in pulmonary pathogens … Read more

Magnolia essential oil fights bacteria and oxidative stress with natural potency

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In lab tests, Magnolia essential oil disrupted harmful bacteria and neutralized free radicals, showing promise as a natural solution for food safety and antimicrobial packaging. Study: Magnolia essential oil: a preliminary exploration of chemical composition and its antimicrobial and antioxidant potential. Image Credit: Elena.Katkova / Shutterstock In a recent study published in the journal Frontiers in Microbiology, … Read more

Low vitamin D levels damage erectile health via superoxide surge, study finds

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Low vitamin D doesn’t just weaken bones; it can sabotage sexual health, disrupt key biological defenses, and make common ED treatments less effective, according to new research. Study: Vitamin D deficiency induces erectile dysfunction: Role of superoxide and Slpi. Image Credit: Lightspring / Shutterstock In a recent study published in the British Journal of Pharmacology, researchers found … Read more

Harvard researchers map 70,000 synaptic connections in rat brain

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Harvard researchers have mapped and catalogued more than 70,000 synaptic connections from about 2,000 rat neurons, using a silicon chip capable of recording small yet telltale synaptic signals from a large number of neurons. The research, published in Nature Biomedical Engineering, is a major advance in neuronal recording and may help bring scientists a step closer to … Read more

AI deciphers intracellular signals from extracellular recordings in heart cells

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A team of researchers led by the University of California San Diego and Stanford University has developed a noninvasive method to monitor the electrical activity inside heart muscle cells from the outside, avoiding the need to physically penetrate the cells. The method, published on Jan. 14 in Nature Communications, relies on recording electrical signals from … Read more

Adenosine Deaminase 2 Regulates Toll-Like Receptor 9 Activation by Nucleic Acids

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Immune System Regulator Uncovered: ADA2’s ⁤Surprising Role ​in Fighting Infections New research reveals a previously unknown ‍function for the enzyme adenosine deaminase 2​ (ADA2), highlighting its crucial role in regulating the body’s ‍immune response to infections. Scientists have long known ADA2 for its ability to break​ down ​adenosine,a molecule involved in various bodily functions. However,a … Read more