Researchers have found that targeted delivery of messenger RNA (mRNA) can restore sperm production and fertility in genetically infertile male mice. The findings, published today in Stem Cell Reports, demonstrate that transient mRNA treatment restored sperm production and enabled the birth of healthy offspring. Up to 10% of couples worldwide are affected by infertility, according … Read more
Share this Article You are free to share this article under the Attribution 4.0 International license.
Increasing paternal age has been linked to elevated health risks for the next generation, including higher risks of obesity and stillbirth. But what drives this increased risk remains unknown. Most research into this link focuses on how the DNA inside sperm changes with age. But sperm carry other molecules as well, including a diverse array … Read more
A new research paper was published in Volume 17, Issue 12 of Aging-US on December 29, 2025, titled “Age-specific DNA methylation alterations in sperm at imprint control regions may contribute to the risk of autism spectrum disorder in offspring.” The study – selected as our Editors’ Choice for January, 2026 – was led by first authors Eugenia Casella and Jana … Read more
Emerging evidence links regular sugary drink intake to impaired sperm quality and DNA damage. Find out why experts recommend reducing SSBs for reproductive health. Recommendations for reducing the impact of SSBs on sperm health. Research shows that regular consumption of sugar-sweetened beverages (SSB) is associated with adverse effects on male reproductive health, primarily through hormonal … Read more
Could a simple mineral hold the key to solving unexplained male infertility? New findings suggest that phosphate, vital for energy and testicular function, may play a surprising role in sperm health, offering a new angle for treatment. Image Credit: Babul Hosen / Shutterstock Men with fertility issues have lower levels of phosphate in the blood than average, … Read more
In a study of more than 5,000 mothers and their children, exposure to air pollution during the three months before pregnancy predicted higher child body mass index (BMI) and related obesity risk factors up to two years of age. Findings from the study, which was supported by the National Institute of Environmental Health Sciences, were … Read more
Childhood stress can impact the epigenetic profile of sperm. These results may also have practical implications for future generations through epigenetic inheritance, as many of the observed epigenetic associations are related to brain development. This ground-breaking discovery has been made in the FinnBrain study at the University of Turku, Finland, in collaboration with researchers from … Read more