Pregnancies occurring during or after initial C3 glomerulopathy (C3G) presentation may be at an increased risk of adverse renal and obstetric events, according to findings from a recent study.1 Results from the retrospective analysis of patient data from the University of Iowa’s C3G Natural History Study highlight an increased risk of preeclampsia, prematurity, and renal … Read more
Scientists have identified mutated immune cell clones that could point to improved treatment for refractory celiac disease. Researchers at the Garvan Institute of Medical Research and UNSW Sydney have discovered why some people with celiac disease continue to suffer debilitating symptoms despite strictly avoiding gluten. The study, published in Science Translational Medicine, used cutting-edge single-cell … Read more
Researchers at Washington University School of Medicine in St. Louis have upended decades-old dogma of how connections between brain cells are rearranged during states of heightened vigilance or attention. The team found that a brain chemical associated with alertness, attention and learning alters brain connectivity and function not by acting directly on neurons, the cells … Read more
Sagnik Sen, MD, MRCSEd | Image Credit: LinkedIn Findings from a recent study suggest eyes with retinal vein occlusion (RVO) with previous cystoid macular edema (CME) requiring intravitreal treatment are at substantial risk of postoperative macular edema (PME) after uneventful cataract surgery. Of note, this risk increases significantly in patients with diabetes.1 Although PME rates … Read more
A recent systematic review has indicated the safety and efficacy of .19 mg fluocinolone acetonide sustained-release intravitreal implants for treating non-infectious uveitis affecting the posterior segment of the eye (NIU-PS) in real-world scenarios.1 The standard treatment method for NIU is corticosteroids; however, local and/or systemic side effects can constrain their use. Immunosuppressive agents have become … Read more
Elevated lipoprotein(a) [Lp(a)] levels were linked to a higher risk of recurrent atherosclerotic cardiovascular disease (ASCVD) events, like myocardial infarction and stroke, but this threat may be attenuated by intensive low-density lipoprotein cholesterol (LDL-C)-lowering therapy.1 In the largest study to date of people living with CVD and a confirmed Lp(a) measurement, investigators analyzed data from … Read more
Justin and Hailey Bieber’s cryptic social media activity continues. The “Baby” singer flaunted his drug use in an Instagram carousel shared Thursday. Justin, 31, was all smiles in the opening slide as he sat in an armchair with a massive glass bong on his lap. Justin Bieber did not hide his drug use in his … Read more
Researchers from the University of Tokyo have found a way to observe clotting activity in blood as it happens – without needing invasive procedures. Using a new type of microscope and artificial intelligence (AI), their study shows how platelet clumping can be tracked in patients with coronary artery disease (CAD), opening the door to safer, … Read more
Type 1 diabetes (T1D) development in adulthood was linked to an elevated risk of cardiovascular disease (CVD) and death, with diagnosis at age ≥40 years not related to an improved long-term prognosis compared with those diagnosed earlier.1 The registry-based study, using nationwide Swedish data from 2001 to 2022, identified more than 10,000 people diagnosed with … Read more
Just as species adapt over generations, our body’s cells accumulate DNA changes throughout life. Most are harmless, yet a few “driver” mutations give a cell a competitive edge and can spark cancer. Chemotherapy then adds a new evolutionary pressure, encouraging further genetic changes that let tumors bounce back. Researchers at IRB Barcelona have developed DiffInvex, … Read more