Hormone FGF21 reverses fatty liver disease by signaling the brain

A pioneering research study published today in Cell Metabolism details how the hormone FGF21 (fibroblast growth factor 21) can reverse the effects of fatty liver disease in mice. The hormone works primarily by signaling the brain to improve liver function. University of Oklahoma researcher Matthew Potthoff, Ph.D., is the lead author of the study, which … Read more

Our once-thriving market is now a ghost-town – fund cuts and have turned it into a soulless drug haven

AN HISTORIC market could close down after budget cuts left shop owners struggling. Devastated workers at the busy London stalls claim it’s a ghost town after increased rents led to closures and fewer customers. 10 Brixton Village has become a ghost-town after rent increases and business closuresCredit: Ian Whittaker 10 The market contains 179 businesses … Read more

Illicit fentanyl use in the U.S. far higher than previously reported

More Americans use illicit opioids such as fentanyl than previously estimated, highlighting the need for better methods to understand the depths of the opioid crisis, according to a new study. A survey of American adults found that 11% reported illicit opioid use within the past 12 months and 7.5% reported use of illicitly produced fentanyl … Read more

Top News for Healthcare Providers from the Week of 05/04

Welcome to The HCPFive, your go-to roundup for the latest healthcare news and breakthroughs, curated specifically for busy healthcare professionals. Each week, we highlight 5 key developments or headlines from healthcare that you need to know—whether it’s a cutting-edge treatment, regulatory updates, or innovations shaping the future of medicine. This week’s top stories include major … Read more

2 drivers of embattled bus firm test positive for drugs

(UPDATE) TWO drivers of the Solid North Bus, Inc. tested positive for illegal substances during a mandatory drug testing conducted by the Land Transportation Office (LTO), compounding scrutiny on the embattled transport firm following its involvement in a horrific Labor Day crash that claimed twelve lives, including six children, and left more than twenty injured. … Read more

Semaglutide May Effectively Treat Non-Diabetic Nephropathy, Study Finds

Results from a recent study have indicated that semaglutide may serve as an effective therapeutic option for patients who have immunoglobulin A (IgA) nephropathy and overweight or obesity without diabetes who are undergoing conventional treatment regimens. Glucagon-like peptide-1 receptor agonist (GLP-1RA) can significantly decrease the risk of cardiovascular events in patients with or without diabetes. … Read more

Precision Medicine for Soft Tissue Sarcomas | Improved Treatment

Revolutionizing Soft Tissue Sarcoma Treatment with Functional Precision Medicine Soft tissue sarcomas (STS) represent a formidable challenge in oncology. A recent collaborative study involving leading research institutions and a biotech firm has unveiled a promising new strategy for improving treatment outcomes for these rare and aggressive cancers. The findings, published in npj Precision Oncology, highlight … Read more

Cognitive Impairment Prevalence in COPD Population Rising Globally

A recent systematic review and meta-analysis identified an increase in the prevalence of cognitive impairment in the chronic obstructive pulmonary disease (COPD) population, with a variety of confounding factors influencing development.1 Cognitive impairment is measured over a series of degrees in one or more cognitive domains, including orientation, memory, calculations, language, executive function, reasoning, attention, … Read more

New rifamycin drugs fight antibiotic-resistant lung infections more effectively

Modified antibiotics beat a stubborn lung pathogen and dodge metabolic landmines, offering new hope for patients with HIV, cystic fibrosis, and TB co-infections. Study: Next-generation rifamycins for the treatment of mycobacterial infections. Image Credit: Kateryna Kon / Shutterstock The rise of drug-resistant bacteria is a major health crisis. Moreover, the development of antibiotic resistance in pulmonary pathogens … Read more

Rising antibiotic resistance threatens UTI treatment in Malawi

A growing resistance to antibiotics is complicating the treatment of urinary tract infections (UTIs) in Malawi, with new research revealing that nearly half of women presenting with symptoms at a major referral hospital had infections resistant to multiple drugs. The study, conducted by researchers at Mzuzu University and published in the National Library of Medicine, found a … Read more