Machine learning model predicts liver cancer risk with high accuracy

Bottom Line: A machine learning model that analyzes patient demographics, electronic health record data, and routine blood test results predicted a patient’s risk of hepatocellular carcinoma (HCC), the most common type of liver cancer, with high accuracy. Journal in Which the Study was Published: Cancer Discovery, a journal of the American Association for Cancer Research … Read more

Cannabis use in adolescence associated with higher rates of psychiatric disorders

Adolescents who use cannabis could face a significantly higher risk of developing serious psychiatric disorders by young adulthood, according to a large new study published today in JAMA Health Forum. The longitudinal study followed 463,396 adolescents ages 13 to 17 through age 26 and found that past-year cannabis use during adolescence was associated with a … Read more

Duplicate medical records linked to higher hospital death risk

Patients with duplicate medical records are 5 times more likely to die after being admitted to hospital and 3 times more likely to require intensive care than those with a single medical record, reveals US research published online in the journal BMJ Quality & Safety. The findings prompt the researchers to call for improvements in data … Read more

How It Works in Real Life

Everyone agrees primary care physicians (PCPs) need to work together with cardiologists when caring for patients with heart disease, diabetes, and sometimes both conditions. Medscape Medical News asked for examples of PCP-to-cardiologist referrals that were successful — or not. Here are three success stories and one that could have turned out better. Diabetes, Hypertension, New-Onset Raynaud’s…at … Read more

New studies offer hope for easing primary care doctor burnout

America’s primary care doctors are burning out, cutting back their hours, and leaving their practices early, driven in part by the demands of handling the flood of digital messages from their patients. But a trio of new University of Michigan studies offer hope for easing this crisis, and improving both the care that patients get … Read more

Esketamine Combo Bests SSRIs for TRD in Head-to-Head Trial

Esketamine combined with a serotonin-norepinephrine reuptake inhibitor (SNRI) for treatment-resistant depression (TRD) was linked to significantly lower rates of several adverse outcomes than esketamine plus a selective serotonin reuptake inhibitor (SSRI), new research showed. Prior research has suggested that esketamine combined with either antidepressant is effective for TRD. But whether an add-on SNRI would yield … Read more