LOS ANGELES — Saffron may help treat sexual dysfunction related to selective serotonin reuptake inhibitors (SSRIs), new research suggests. Results of a preliminary new review found saffron, a spice derived from the flower of Crocus sativus, commonly known as the “saffron crocus,” reduced erectile dysfunction in men and boosted arousal in women. Jeremy Wolfe, MD … Read more
LOS ANGELES — Mood episodes in patients with bipolar disorder (BD) that occur more frequently or severely during specific seasons — known as seasonality patterns — are associated with treatment response and different characteristics and subtypes of the disorder, new research suggested. In a study of more than 1700 patients with BD, investigators found links … Read more
A new social media trend is making headlines: Methylene blue is being touted as a cognitive booster and antiaging miracle. Influencers such as Ben Greenfield are promoting the use of this chemical to enhance brain performance, strengthen the immune system, and even prevent cancer without providing scientific evidence. Researchers have warned that methylene blue can … Read more
Esketamine combined with a serotonin-norepinephrine reuptake inhibitor (SNRI) for treatment-resistant depression (TRD) was linked to significantly lower rates of several adverse outcomes than esketamine plus a selective serotonin reuptake inhibitor (SSRI), new research showed. Prior research has suggested that esketamine combined with either antidepressant is effective for TRD. But whether an add-on SNRI would yield … Read more
TOPLINE: Low levels of soluble neuropilin-1 (sNRP-1) were associated with depression in patients with newly diagnosed type 2 diabetes (T2D), with the association remaining consistent across all age groups. METHODOLOGY: The NRP-1 receptor is an essential transmembrane glycoprotein involved in the development of the nervous and cardiovascular systems, as well as immune regulation, and may … Read more
The French Society for Biological Psychiatry and Neuropsychopharmacology has unveiled revised guidelines for the management of depressive disorders with partial and resistant responses to treatment. The update was presented at the 43rd edition of the Congrès de l’Encéphale, France’s leading psychiatric event, held in Paris from January 22 to 24, 2025. Professor Antoine Yrondi, a … Read more
Depression poses serious health concerns, particularly during pregnancy and after childbirth. Recent data from the United States are alarming, showing that nearly half of women stop taking antidepressants during pregnancy. A study published in JAMA Network Open highlights this trend, which may have serious consequences for both mothers and their children. The study, led by … Read more
A new Cochrane review confirmed that antidepressants, including selective serotonin reuptake inhibitors (SSRIs) and serotonin-noradrenaline reuptake inhibitors (SNRIs), are superior to placebo in adults with generalized anxiety disorder (GAD) and have comparable study dropout rates. However, the long-term impact of antidepressants on GAD remains unclear. “We have high confidence that antidepressants are more effective than … Read more