Remdesivir & COVID-19: Does Frailty Affect Treatment Outcomes in Seniors?

The COVID-19 pandemic brought a surge of research into potential treatments and for many, especially those with older loved ones, remdesivir emerged as a frequently discussed option. However, as with… The post Remdesivir & COVID-19: Does Frailty Affect Treatment Outcomes in Seniors? appeared first on News Directory 3. Source link

One-year body weight loss and gain as independent predictors of frailty-related outcomes and mortality in an aging Japanese population

Fujii, H. et al. Yubi-wakka (finger-ring) test: A tool to detect prefrailty in elderly populations, a pilot study. J. Clin. Med. Res. 11, 623–628 (2019). Google Scholar  Fujii, H. et al. Sarcopenia and coexistent risk factors detected using the Yubi-wakka (finger-ring) test in adults aged over 65 years in the public annual health checkup in … Read more

Inflammatory markers and clinical factors as key independent risk factors for frailty: a retrospective study | BMC Geriatrics

Frailty presents a significant challenge in the context of a rapidly growing aging population, which is marked by heightened vulnerability to stressors due to an accelerated decline in physiological function, placing a significant burden on the healthcare system [12]. Frailty in older adults is associated with various factors, such as age, gender, BMI, comorbid chronic … Read more

Prevalence of sarcopenia and its association with frailty and malnutrition among older patients with sepsis-a cross-sectional study in the emergency department | BMC Geriatrics

Demographics, clinical characteristics, and geriatric syndromes The demographics and clinical characteristics in the groups with and without sarcopenia are listed in Table 1. A total of 602 older patients with sepsis (218 with and 384 without sarcopenia) were included. The median age of the participants was 78 (IQR, 16) years, 332 (55.1%) were men, and the … Read more

Metabolic profiling of frailty, associations with type 2 diabetes and interaction with genetic susceptibility | Cardiovascular Diabetology

Study population Detailed information of the study design has been presented previously [15]. Briefly, the UK Biobank enrolled over 0.5 million participants aged 37 to 73 years from 22 sites across the UK between 2006 and 2010, and collected extensive information at recruitment, including data from touchscreen questionnaires, physical examinations, biological samples, and longitudinal follow-up for … Read more

Many Definitions, No Easy Solutions

SAN FRANCISCO — Frailty is hard to define and hard to distinguish from the effects of illness, injury, and medical interventions, but the frailty of patients in the intensive care unit (ICU) can have profound effects on outcomes, including the risk for mortality. In a scientific symposium on frailty in the ICU, presented during the … Read more

Social isolation in relation to the incidence and dynamic progression of frailty in the oldest old: a trajectory analysis of a nationwide cohort | BMC Public Health

Zeng Y, Feng Q, Hesketh T, Christensen K, Vaupel J. Improvements in survival and activities of daily living despite declines in physical and cognitive functioning among the oldest-old in China – Evidence from a cohort study. Lancet. 2017;389:1619–29. PubMed  PubMed Central  Google Scholar  Bevilacqua G, Jameson KA, Zhang J, Bloom I, Fuggle NR, Patel HP, … Read more

Missed Red Flags in Rheumatic Care

Fatigue and frailty, two common comorbidities of inflammatory rheumatic diseases, often receive insufficient attention in rheumatologic care settings. Fatigue significantly reduces quality of life, while frailty is associated with numerous risks and is not limited to older adults, according to Klaus Krüger, MD, head of the St. Bonifatius Rheumatology Practice Center in Munich, Germany. Speaking … Read more

Associations of frailty and cognitive impairment with all-cause and cardiovascular mortality in older adults: a prospective cohort study from NHANES 2011–2014 | BMC Geriatrics

Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K. Frailty in elderly people. Lancet. 2013;381(9868):752–62. Article  PubMed  Google Scholar  Hoogendijk EO, Afilalo J, Ensrud KE, Kowal P, Onder G, Fried LP. Frailty: implications for clinical practice and public health. Lancet. 2019;394(10206):1365–75. Article  PubMed  Google Scholar  Dent E, Martin FC, Bergman H, Woo J, Romero-Ortuno … Read more

Retrospective Analysis Shows Frailty Leads to Worsened Outcomes After Surgery in Gynecologic Cancers

Gynecologic Cancer| Image Credit: © Katsyarina – stock.adobe.com Frailty and elder age may contribute to worsened postoperative outcomes, regardless of following enhanced recovery after surgery (ERAS) protocols in patients undergoing major gynecologic oncology surgery, according to retrospective data presented at the 2025 SGO Winter Meeting. Data from the study revealed that patients 65 years of … Read more