Guanine

Unexpected function of gene network in gut microbes revealed

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Could a gene regulatory network in gut microbes have evolved its elaborate and tightly regulated molecular machinery only to pump out antibiotics indiscriminately? Researchers from the Institute of Science and Technology Austria (ISTA) show this is an auxiliary function. By maintaining basal levels of genetic activity when the network is in its OFF state, these … Read more

APOBEC proteins linked to DNA repeat expansion in Huntington’s disease

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People genetically susceptible to Huntington’s disease often see their movement, mood, and cognition decline slowly over time.  The cause is related to expansion of repeating DNA units, in which specific strings of genetic code-in this case, a series of cytosine-adenine-guanine nucleotides, or CAG, on one strand of the DNA and cytosine-thymine-guanine, or CTG, on the complementary … Read more