Air pollution may triple heart disease cases by 2045, study finds

Despite advances in air quality, global heart disease deaths tied to particulate pollution have soared, especially for seniors and in developing nations, with women facing the sharpest future rise. Study: Global cardiovascular disease burden attributable to particulate matter pollution, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2045 – Image … Read more

Nontraditional risk factors shed light on unexplained strokes in adults younger than 50

Research Highlights: Among adults ages 18-49 (median age of 41 years) who were born with a hole in the upper chambers of their heart known as patent foramen ovale (PFO), strokes of unknown cause were more strongly associated with nontraditional risk factors, such as migraines, liver disease or cancer, rather than more typical factors … Read more

Elevated FGF-23 predicts reduced LAAev and stroke risk in patients with atrial fibrillation

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Current AF management guidelines have introduced the CARE treatment model to strengthen management strategies; in this acronym, the “A” indicates anticoagulation therapy. However, despite anticoagulation, approximately one-third of patients with AF experience ischemic stroke, which is closely associated with factors such as poor adherence … Read more

Study shows potential of uric acid as add-on therapy for stroke

In a preclinical study, rodents treated with uric acid showed improved long-term outcomes after acute ischemic stroke. The findings suggest that the treatment may work as an add-on therapy to standard stroke treatments in humans. The study was funded by the National Institutes of Health (NIH) and published in Stroke. Led by Enrique Leira, M.D., … Read more

Nerinetide shows promise in stroke treatment meta-analysis

The Calgary Stroke Program, a joint University of Calgary and Alberta Health Services initiative at Foothills Medical Centre, has been involved with three papers published this week in The Lancet and Lancet Neurology-the ESCAPE-NEXT trial, the FRONTIER trial, and an individual patient-level meta-analysis across three trials. The studies, in collaboration with NoNO Inc., are focused … Read more

Study finds varying cardiovascular risks associated with different hormonal contraceptives

Certain hormonal contraceptives are associated with a higher stroke and heart attack risk, finds a large study from Denmark in The BMJ today that draws on prescription records to give more precise estimates for different products than previous studies. The highest risk estimates were for oestrogen containing products, in particular the vaginal ring and skin patch. The … Read more

Clot-busting drug alteplase shows promise for stroke treatment up to 24 hours after onset

The clot-dissolving medication, alteplase, improved stroke patients’ recovery by more than 50% when given up to 24 hours after the beginning of an ischemic stroke, according to preliminary late-breaking science presented today at the American Stroke Association’s International Stroke Conference 2025. The conference, in Los Angeles, Feb. 5-7, 2025, is a world premier meeting for researchers and … Read more

Propranolol Linked to Lower Ischemic Stroke Risk in Females with Migraine

Mulubrhan Mogos, PhD, MSc Credit: Vanderbilt University A study found propranolol is associated with a significant reduction in ischemic stroke among females with migraine, indicating propranolol may be beneficial for stroke prevention in high-risk populations. The preliminary findings will be presented at the American Stroke Association International Stroke Conference 2025 in Los Angeles from February … Read more

Epidemiological trends and age-period-cohort effects on ischemic stroke burden across the BRICS-plus from 1992 to 2021 | BMC Public Health

The study examines significant variations in the global burden of ischemic stroke and within BRICS-plus countries from 1992 to 2021. Our analysis indicates a substantial 47.14% increase in the number of DALYs, despite a 33.79% decrease in the age-standardized DALYs rate, with notable discrepancies among the ten BRICS members. These findings highlight the complex epidemiology … Read more