A Rising Threat to Cancer Care

As Hurricane Helene approached western North Carolina, Martin Palmeri, MD, MBA, didn’t anticipate the storm would disrupt practice operations for more than a day or so. But the massive rainfall and flooding damage last September proved to be far more challenging. Despite best efforts by the 13-physician practice, basic treatments for most patients were interrupted … Read more

Study Maps How Exosomes Hijack Blood Formation

TOPLINE: Chronic lymphocytic leukemia (CLL) cell–derived exosomes demonstrated the ability to alter healthy donor cell function and suppress normal blood cell formation. These particles affected monocytes, fibrocytes, and lymphocytes, leading to changes in gene expression and protein levels that may contribute to disease progression. METHODOLOGY: Researchers examined CLL cell–derived exosomes and their effects on healthy … Read more

Can Dx Take a Toll on Mental Health?

TOPLINE: More than half (56.2%) of patients who are newly diagnosed with lymphoma and myeloma experience clinically significant anxiety or depression symptoms, with lower financial satisfaction and medical mistrust increasing anxiety risk. Depression symptoms, present in 27.5% of patients, were linked to significantly lower quality-of-life (QOL) scores. METHODOLOGY: A cross-sectional survey study conducted at Dana-Farber … Read more

Weill Cornell’s Leonard Noted for His ASH List, Patient Care

John Leonard, MD John Leonard, MD, of Weill Cornell Medicine, New York City, has built a devoted following for his “Leonard List” — previews of research to be presented at annual American Society of Hematology (ASH) meetings that are held every December. For example, in November 2024, in the days leading up to ASH 2025, … Read more

Is Obesity in Children With Cancer Tied to Worse Survival?

TOPLINE: Overall, obesity at the time of cancer diagnosis is independently associated with worse survival outcomes in pediatric patients. The association, however, varied by cancer type with the strongest link in those with acute lymphoblastic leukemia and central nervous system (CNS) tumors but with no significant associations found in those with lymphomas or non-CNS solid … Read more