Revitalizing Antibiotic Research: A New Analytical Approach to Fosfomycin Table of Contents Revitalizing Antibiotic Research: A New Analytical Approach to Fosfomycin Fosfomycin: A Potential Weapon Against Resistant Bacteria The Importance of Accurate Bioanalytical Methods Advancement and Validation of a Novel FOS Assay Assay Performance and Reliability Accurate Fosfomycin Quantification: A Novel Assay for Combating Antimicrobial … Read more
Nanomedicines, especially those based on nanoparticles, are revolutionizing healthcare in terms of both diagnostics and therapeutics. These particles, often containing metals like iron or gold, can serve as contrast agents in medical imaging, act as nutritional supplements, and even function as carriers for drug delivery. Thanks to their unique properties plus careful engineering, nanomedicines can … Read more
Key Points Multi-drug resistance (MDR) is a concerning phenomenon among commonly used antibiotics. Fosfomycin (FOS), which is used to treat urinary tract infections and cystitis (bladder infection) in women, is one antibiotic that is being assessed for addressing MDR. A liquid chromatography–tandem mass spectrometry (LC–MS/MS)-based assay for quantifying FOS in MHB was developed and validated. … Read more
Small molecule drugs continue to dominate the drug pipeline in volume terms, but biologic therapeutics are an alternative, and increasingly important, therapeutic class. Within biologics, a growing number of novel modalities are now emerging, with next-generation biologics incorporating the already heterogeneous features that are present in monoclonal antibodies (mAbs) and other proteins, and adding new … Read more
Research led by Valerie Peulon-Agasse, an associate professor from the University of Rouen-Normandy in Rouen, France, sampled root exudates a new ecofriendly method for gas chromatography coupled with high-resolution mass spectrometry (GC-HRMS). Their findings were published in the Journal of Chromatography Open (1). Fresh green soybean plants with roots | Image Credit: © Олег Мальшаков … Read more
In a strategic move for medical research and innovation, Duke-NUS Medical School and the National University of Singapore Yong Loo Lin School of Medicine (NUS Medicine) have launched the Systems Metabolomics center (SysMeC), their first-ever joint research center. This groundbreaking initiative is set to drive cutting-edge metabolomics research, unlocking new ways to detect diseases earlier … Read more
In this interview, NewsMedical speaks with Arvonn Tully and Esther Kieserman from Yokogawa Life Science about how confocal-based high-content imaging is advancing core facility research and improving data reliability. Could you introduce yourselves and share your background, particularly your work with confocal-based high-content imaging and analysis? Esther Kieserman (EK): I have worked in the microscopy … Read more