Researchers show red blood cells drive better glucose tolerance at high altitude

New research reveals how hypoxia-driven red blood cell adaptations may reshape glucose regulation, offering fresh insight into diabetes biology and potential therapeutic strategies. Study: Red blood cells serve as a primary glucose sink to improve glucose tolerance at altitude. Image Credit: nobeastsofierce / Shutterstock In a recent study published in the journal Cell Metabolism, researchers investigated … Read more

Web-based cytometry atlas reveals immune signatures across pancreatic cancer treatments

Oncologists have achieved some immune system responses in patients with pancreatic cancers using various combinations of vaccines and immune checkpoint inhibitor drugs, but it’s not always clear which therapy is inducing what type of response. To help drive further study, investigators from the Johns Hopkins Kimmel Cancer Center have made public a free, web-based atlas … Read more

mRNA transfection in T-cells

Sponsored Content by SartoriusReviewed by Maria OsipovaApr 30 2025 This research investigates how to optimize mRNA transfection in human T-cells utilizing the jetMESSENGER® transfection reagent. By using advanced bioanalytical instruments like the Incucyte® Live-Cell Analysis System and the iQue® High-Throughput Screening platform, Sartorius detected settings that improve T-cell viability, transfection efficiency, and eGFP expression alike. … Read more

Fish oil supplements beat oily fish at reducing harmful blood vesicles

A high-dose fish oil supplement slashed clot-promoting blood vesicles in healthy adults—outperforming oily fish and pointing to EPA as the key driver behind these cardiovascular benefits. Accepted manuscript: High dose fish oil supplements are more effective than oily fish in altering the number and function of extracellular vesicles in healthy human subjects: A randomized, double-blind, … Read more

Scientists uncover how a sugar shield in brain blood vessels protects against aging and disease

Scientists uncover how the breakdown of a critical sugar-rich layer in brain blood vessels accelerates aging and disease—offering a new therapeutic target to restore brain health. Study: Glycocalyx dysregulation impairs blood–brain barrier in ageing and disease. Image Credit: ART-ur / Shutterstock A recent study published in the journal Nature showed that the dysregulation of the brain endothelial … Read more

Confocal-based high-content imaging in advancing core facilities

In this interview, NewsMedical speaks with Arvonn Tully and Esther Kieserman from Yokogawa Life Science about how confocal-based high-content imaging is advancing core facility research and improving data reliability. Could you introduce yourselves and share your background, particularly your work with confocal-based high-content imaging and analysis? Esther Kieserman (EK): I have worked in the microscopy … Read more