Lifestyle care in primary clinics allows for safe diabetes deprescribing

A new research study provides real-world evidence that deprescribing glucose‑lowering medications is both feasible and safe when patients with type 2 diabetes receive lifestyle‑informed care in primary care settings. The retrospective chart review, published in the Journal of Clinical Medicine, examined electronic health records from 650 adults with type 2 diabetes receiving care at two … Read more

Antidepressant fluvoxamine reduces long COVID fatigue in clinical trial

A major international trial suggests that a widely available antidepressant may help ease one of long COVID’s most disabling symptoms, bringing patients and clinicians closer to a practical treatment option. A global research team co-led by McMaster University has identified one of the first medications shown to meaningfully reduce fatigue in people living with long … Read more

Everday diabetes medicine linked to less progression of age-related macular degeneration

Doctors have found that metformin, an everyday medicine for diabetes, is associated with less progression of age-related macular degeneration (AMD), the commonest cause of blindness in western countries. People with diabetes over the age of 55 years taking metformin were 37% less likely to develop the intermediate stage of AMD over a five year period … Read more

Sex-specific analysis uncovers unique disease pathways and treatment implications

Biological differences between women and men led to variations in the appearance and progression of many diseases, which influenced diagnosis and response to treatments. These differences also affected the relationship between diseases, as they generated different combinations, risks, and patterns of joint appearance depending on sex. However, the biological mechanisms that explained these associations remained … Read more

New findings highlight a shifting landscape for weight loss and glucose managing medications

When it comes to managing weight loss and type 2 diabetes with medications, research shows that it’s out with the old and in with the new. Investigators from Mass General Brigham looked at claims data from nearly 2 million people between 2021 and 2023 and their findings highlight a shifting landscape for weight loss and … Read more

Study reveals how healthy stem cells transform into cancer cells

Nearly 60,000 people are diagnosed with oral cancer in the U.S. every year, according to the American Cancer Society, and the rate of new cases continues to rise. Now, researchers at University of California San Diego have discovered how healthy stem cells are transformed into cancer stem cells in the earliest stages of the disease. … Read more