Lifestyle care in primary clinics allows for safe diabetes deprescribing

A new research study provides real-world evidence that deprescribing glucose‑lowering medications is both feasible and safe when patients with type 2 diabetes receive lifestyle‑informed care in primary care settings. The retrospective chart review, published in the Journal of Clinical Medicine, examined electronic health records from 650 adults with type 2 diabetes receiving care at two … Read more

ACLM launches project remission for Type 2 diabetes

The American College of Lifestyle Medicine (ACLM) announces the launch of Project Remission: A Lifestyle Medicine Approach to Type 2 Diabetes, a national digital film series developed in partnership with Content With Purpose (CWP). Premiering during a live webinar featuring experts in the field at noon CT today, with the full series also launching digitally, the … Read more

Large Study Shows Genetic Risk Results Can Be Returned to Thousands of Patients—With Caveats

A new study published in the American Journal of Human Genetics offers a look at how genetic risk information can be returned to patients at scale—and where health systems still fall short. The research, conducted through the eMERGE network, a multi-site genomic medicine initiative, tracked the return of genome-informed risk assessments to nearly 24,000 adults … Read more

Father’s nicotine use may increase diabetes risk for offspring

A mouse study found that a father’s nicotine exposure can affect the offspring’s ability to process sugar and may contribute to diabetes risk, according to new research published in the Journal of the Endocrine Society. An estimated 40.1 million people in the United States have diabetes, according to the U.S. Centers for Disease Control and Prevention. Having diabetes … Read more

New fragmentome technology can detect early liver fibrosis and cirrhosis

Researchers at the Johns Hopkins Kimmel Cancer Center report that an artificial intelligence (AI)-based liquid biopsy test using genome-wide cell-free DNA (cfDNA) fragmentation patterns and repeat landscapes can detect early liver fibrosis and cirrhosis, and may also reveal signals of broader chronic disease burden. The research was supported in part by the National Institutes of Health, and … Read more

Single prenatal exposure to fungicide linked to disease across 20 generations

A single exposure to a toxic fungicide during pregnancy can increase the risk of disease for 20 subsequent generations – with inherited health problems worsening many generations after exposure. Those are the findings of a new Washington State University study of rats that expands the understanding of how long the intergenerational effects of toxic exposure … Read more

Obesity’s role in shared genetic risks of chronic diseases

A sweeping genetic analysis reveals when obesity is the common thread linking chronic diseases, and when other biology is to blame. Study: Genetics identifies obesity as a shared risk factor for co-occurring multiple long-term conditions. Image credit: MaskaRad/Shutterstock.com A recent study in Communications Medicine completed a genetic analysis to determine whether body mass index (BMI) affects … Read more

Long-Term Keto Diet Risks Raise Questions for Metabolic Health

A long-term study published in Science Advances has found that while a ketogenic diet limited weight gain in mice, prolonged adherence triggered metabolic disruptions, including impaired insulin secretion, fatty liver disease and elevated blood lipids, raising questions about the diet’s long-term safety as it continues to gain popularity for weight loss and metabolic health. The … Read more

PFAS exposure increases gestational diabetes risk

A comprehensive review of nearly 130 studies shows the strongest evidence to date that “forever chemicals” are associated with gestational diabetes, while underscoring uncertainty around other diabetes outcomes and the need for more prospective research. Study: Associations of perfluoroalkyl and polyfluoroalkyl substances with markers of glycaemic control, insulin secretion and sensitivity, and diabetes risk: a … Read more

GLP-1 Drugs & Eye Disease Risk: New Study Findings

Archyde Glp-1 Diabetes Drugs Linked to Increased Risk of Macular Degeneration in New Study A Recent Observational Study Has Uncovered a Low But Noticeable Increase In The risk Of Age-Related Eye Disease, Specifically Neovascular Age-Related macular Degeneration (Namd), Among People With Diabetes Who Are using Glp-1 Drugs. This Finding Adds To Existing Concerns About The … Read more