Sepsis

Construction and validation of a prediction model for short-term mortality risk in elderly patients with sepsis: a retrospective study | BMC Infectious Diseases

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The targeted population of this study was patients with sepsis aged ≥ 65 years. The patients were divided into the survival group and the death group based on their short-term (< 30 days) outcomes at discharge. Patients in the death group exhibited lower levels of ALB, PCT, WBC, NEUT count, high-sensitivity CRP, ALT, and vitamin C positivity rates … Read more

Prevalence of sarcopenia and its association with frailty and malnutrition among older patients with sepsis-a cross-sectional study in the emergency department | BMC Geriatrics

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Demographics, clinical characteristics, and geriatric syndromes The demographics and clinical characteristics in the groups with and without sarcopenia are listed in Table 1. A total of 602 older patients with sepsis (218 with and 384 without sarcopenia) were included. The median age of the participants was 78 (IQR, 16) years, 332 (55.1%) were men, and the … Read more

Stress hyperglycemia ratio as a mortality predictor in non-diabetic septic patients: a retrospective cohort analysis | BMC Infectious Diseases

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Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The third international consensus definitions for Sepsis and septic shock (Sepsis-3). JAMA. 2016;315(8):801–10. https://doi.org/10.1001/jama.2016.0287. Article  CAS  PubMed  PubMed Central  Google Scholar  van der Poll T, Shankar-Hari M, Wiersinga WJ. The immunology of sepsis. Immunity. 2021;54(11):2450–64. https://doi.org/10.1016/j.immuni.2021.10.012. Article  CAS  PubMed  Google Scholar  … Read more

Association between advanced lung cancer inflammation index and mortality in critically ill septic patients: analysis of the MIMIC-IV database | BMC Infectious Diseases

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Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315(8):801–10. Article  CAS  PubMed  PubMed Central  Google Scholar  Reinhart K, Daniels R, Kissoon N, Machado FR, Schachter RD, Finfer S. Recognizing … Read more

A retrospective analysis of the correlation between the glucose-to-albumin ratio and 28-day mortality in sepsis patients | BMC Infectious Diseases

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Basic characteristics of septicemia patients Table 1 presents the basic characteristics of septic patients in this study. There were a total of 6731 participants, with 2907 females (43.2%) and 3824 males (56.8%), and the average age was 62.9 ± 16.7 years. The 28-day mortality rate after admission for these septic patients was 24.7%. The study data … Read more

Study reveals nursing care gaps in Black-serving hospitals

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A new study – just published in Nursing Research – has uncovered concerning disparities in patient outcomes, specifically related to nursing care, within hospitals that predominantly serve Black communities. The research, which analyzed data from over 3,000 hospitals across the United States, reveals that these Black-serving hospitals (BSHs) exhibit significantly higher rates of specific adverse … Read more

New thromboinflammation-on-a-chip model may revolutionize treatment of harmful blood clots

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Blood clots are associated with life-threatening conditions such as sepsis, sickle cell disease, heart attack, and stroke.  However, new research from Emory University may revolutionize how clinicians understand and treat these harmful blood clots, or thrombi, a byproduct of a condition called thromboinflammation. In a groundbreaking study published in Nature, researchers have discovered the potential to … Read more

Pandemic Lockdowns Goosed Group A Strep Strains

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Investigators in Canada have discovered that molecular changes to an infectious bacterium (Group A Streptococcus pyogenes [GAS]) underlie a post-pandemic surge of coinfections with a respiratory diagnosis, prompting one expert to suggest lockdowns during the pandemic might have created an immunity deficiency in hosts while at the same time helping the bacteria create newly virulent … Read more

Revolutionary AI Model Accurately Predicts Sepsis Mortality in ICU

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Archyde AI Revolutionizes sepsis Prediction in ICUs, Promising Improved Patient Outcomes Table of Contents 1. AI Revolutionizes sepsis Prediction in ICUs, Promising Improved Patient Outcomes 2. The Sepsis Crisis: A Race Against Time 3. A Breakthrough in Predictive Modeling: The Transformer-Based AI 4. How the AI Model Works: A Two-Pronged Approach 5. Identifying Key Predictors … Read more

New AI model predicts sepsis mortality in the ICU with high accuracy

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Sepsis is one of the deadliest conditions in intensive care units (ICUs), triggered by the body’s out-of-control response to infection. Despite medical advancements, its in-hospital mortality rate still hovers between 20% and 50%. The challenge lies in early identification—sepsis is highly dynamic, and current scoring systems like APACHE-II and SOFA are not specifically designed to … Read more