TOPLINE: Janus kinase (JAK) inhibitors were associated with more infections, particularly herpes infections, in patients with atopic dermatitis (AD) compared with biologics, in a cohort study. METHODOLOGY: A prospective, multicenter observational study included 1793 patients (age, ≥ 12 years) with moderate to severe AD from the Dutch BioDay registry between October 2017 and July 2024. … Read more
Is obesity among the most misunderstood, misclassified, and mistreated diseases? Over the past 30 years, researchers have not only identified a key hormone (leptin) that helps regulate appetite and body weight, but they’ve also determined the biologic underpinnings (eg, altered central nervous system pathways associated with energy balance) and discovered that obesity is often genetically … Read more
The French National Agency for the Safety of Medicines and Health Products has alerted healthcare professionals and parents about a concerning trend known as the “Paracetamol Challenge” that is gaining popularity, particularly on social media, among children and adolescents. This challenge involves the deliberate ingestion of toxic doses of paracetamol to evaluate one’s resistance and … Read more
The less-is-more approach continues to gain momentum with more awareness on skin health and the need to protect the all-important skin barrier. This is driving consumers towards a more minimalist beauty routine, which embraces simple routines with multi-functional products that does not overload the skin. At the same time, the skinification movement shows no signs … Read more
Glow Recipe expands hybrid range on the back of high consumer demand Glow Recipe expands its range of tinted serums with s blush-serum hybrid following strong consumer demand for multi-functional beauty solutions. The US-based skin care brand announced the launch of the Watermelon Glow Niacinamide Dewy Flush, a tinted cheek serum, at their Glow Conference … Read more
TOPLINE: During the COVID-19 pandemic, prescriptions for hypnotic medications notably increased among children, particularly among those aged between 6 and 11 years for prolonged-release melatonin and in adolescents for Z-drugs such as zolpidem; this increase persisted until the end of the study in December 2023. METHODOLOGY: Researchers conducted a cross-sectional analysis of national dispensing data … Read more
The self-collection of sexually transmitted infection (STI) tests circumvents barriers that deter adolescents and young adults (AYAs) from seeking clinic-based reproductive healthcare, a text-based national survey suggested. Okeoma O. Mmeje, MD, MPH “The autonomy and confidentiality offered by self-collection may empower AYAs to take charge of their sexual health without fear of judgment or social … Read more
A subtype of molecular bacterial vaginosis (BV) increases risk for Chlamydia trachomatis (CT) infection among Black and Hispanic adolescents and young women, according to investigators. This finding adds to a growing body of evidence that the cervicovaginal microbiome (CVM) plays a central role in the natural history of CT infection and should be explored as … Read more
Archyde > Long-Term Efficacy and Safety of Ritlecitinib in Alopecia Areata Table of Contents 1. Long-Term Efficacy and Safety of Ritlecitinib in Alopecia Areata 2. Promising Results: Hair Regrowth Sustains Over Time 3. Safety Profile: Favorable Despite Side Effects 4. What Are the Key Differences Between the ALLEGRO-LT Study and Previous Ritlecitinib Trials for AA? … Read more
TOPLINE: Ritlecitinib demonstrates long-term improvements in regrowth of scalp hair, eyebrows, and eyelashes at 24 months in adults and adolescents with alopecia areata (AA) and ≥ 25% scalp hair loss. METHODOLOGY: Researchers evaluated outcomes in 449 de novo adult and adolescent patients (mean age, 32.9 years) with AA and ≥ 25% scalp hair loss, enrolled … Read more