Tropical Medicine

Global, regional, and national trends in chronic kidney disease burden (1990–2021): a systematic analysis of the global burden of disease in 2021 | Tropical Medicine and Health

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Global CKD burden There was substantial variation in the age-standardized incidence rate (ASIR) and age-standardized mortality rate (ASMR) of CKD across the world in 2021 (Fig. 1; Figure S1). The highest ASIR was observed in Saudi Arabia (495.8 per 100,000 population), followed by Qatar (467.4 per 100,000) and the United Arab Emirates (466.4 per 100,000). In … Read more

Haematological markers as predictive tools for tuberculosis in PLHIV: a retrospective cohort study in Gujarat, India | BMC Infectious Diseases

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Our study demonstrates the potential utility of hematological parameters, particularly the monocyte-lymphocyte ratio (MLR) and anemia status, in predicting tuberculosis (TB) disease among people living with HIV (PLHIV). These findings contribute to a growing body of evidence supporting the use of readily available hematological markers in TB risk assessment and management in HIV-positive populations. Furthermore, … Read more

Prevalence of human papillomavirus (HPV) genotypes in patients with clinical symptoms in Kermanshah, western Iran: a cross-sectional study | BMC Infectious Diseases

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Study population and overall prevalence of HPV The mean ages of the females and males were 37.55 ± 10.36 (10–72) and 35.14 ± 8.379 (17–60) years, respectively. Most of the referred patients were in the 21–50 years age groups, which are the reproductive age and sexually active groups (Table 1). Among the 872 patients, 340 patients (38.9%) were positive for … Read more

Parasitological and microbiological assessment of contact lens storage cases: a survey of asymptomatic lens student wearers from five medical specialties in Tunisia, North Africa | BMC Infectious Diseases

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Demographic, clinical and behavioral characteristics of the studied population The mean age of all participants was 22.8 years, with a standard deviation of 2.4 years and extremes ranging from 18 to 31 years. A predominance of females was reported (n = 105, 95%), which corroborates the findings of previous studies in which most lens wearers were females … Read more

Molecular identification of plasmid-mediated quinolone resistance genes among klebsiella pneumoniae clinical isolates from southwest Iran | BMC Infectious Diseases

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The widespread use of fluoroquinolones has resulted in the emergence of quinolone-resistant Enterobacteriaceae isolates including K. pneumoniae [6]. In this study, the antibiotic susceptibility rate of QRKP to different antibiotics including four quinolones was tested. Then, the frequency of seven PMQR genes in resistant isolates was investigated. To the best of our knowledge, this was … Read more

Prevalence, perception of risk and mycobacterium tuberculosis control practices among healthcare workers in HIV care and treatment centres in North Central Nigeria | BMC Infectious Diseases

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HWs are often at an increased risk of developing infections due to their proximity to infected patients, and this risk is usually higher in high-risk settings [2, 9]. To this end, our study measured the perception of risk towards acquisition of TB and correlates this with the actual TB infection rates among HW working in … Read more

A diagnostic model for sepsis using an integrated machine learning framework approach and its therapeutic drug discovery | BMC Infectious Diseases

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Brit L, Gottlieb M. Emergency medicine updates: management of sepsis and septic shock. Am J Emerg Med, 2025, 90(0). Andrew Rhodes LE, Evans W, Alhazzani et al. Surviving Sepsis Campaign: International guidelines for Management of Sepsis and Septic Shock: 2016. Intensive Care Med, 2017, 43(3). Evans L, Rhodes A, Alhazzani W, et al. Surviving sepsis … Read more

Prevalence of post-pandemic SARS-CoV-2 in patients with respiratory syndrome in Brazzaville, Republic of the Congo | BMC Infectious Diseases

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease has been prevalent worldwide since December 2019 and has caused a significant loss of life. SARS-CoV-2 primarily affects the respiratory system with a wide range of clinical manifestations, from mild to severe, particularly in elderly and immunocompromised patients [1, 2]. The first alert was an outbreak of … Read more

Unravelling the mode of action of the Tres Cantos Antimalarial Set (TCAMS): investigating the mechanism of potent antimalarial compounds potentially targeting the human serotonin receptor | Malaria Journal

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Characterization of the IC50 values and evaluation of the cytotoxicity of the compounds in the TCAMS library The IC50 values for each compound were determined in asynchronous cultures of P. falciparum 3D7 exposed to various concentrations of the test compounds (0.0019–2 μM). Parasitaemia was assessed by flow cytometry via a double-labelling technique: SYBR Green-labelled DNA and … Read more

Study on the aggregation patterns of fleas parasitizing the great gerbil (Rhombomys opimus) in the Junggar Basin plague natural focus | Parasites & Vectors

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Flea composition parasitizing the great gerbil A total of 90 flea investigations were conducted on the great gerbils in three subzones. Consequently, a total of 2258 great gerbils were captured, from which 17,780 fleas belonging to 19 species of 10 genera and 8 families were collected. The mean flea infestation rate of the great gerbils … Read more