New algorithm enables precise subtyping of metabolic liver disease

Metabolic-associated steatotic liver disease (MASLD) is a clinically heterogeneous condition with highly variable outcomes affecting more than 30% individuals globally. The disease is conventionally staged by histological progression, ranging from simple steatosis to metabolic dysfunction-associated steatohepatitis (MASH) and ultimately fibrosis or cirrhosis. Beyond liver-related outcomes, MASLD significantly elevates the risk of extrahepatic complications, including cardiovascular … Read more

How are GLP-1 drugs reshaping treatment for obesity, diabetes, and heart disease?

A sweeping Lancet review reveals how modern incretin-based drugs are reshaping treatment for obesity and diabetes, delivering powerful weight loss while simultaneously protecting the heart, kidneys, and metabolic health. Review: GLP-1 receptor agonists and next-generation incretin-based medications: metabolic, cardiovascular, and renal benefits. Image Credit: Gecko Studio / Shutterstock In a recent review published in The … Read more

Prior COVID infection increases kidney disease risk

Approximately one in seven adults in the United States has kidney disease, where the organs responsible for filtering waste and excess water from the blood are damaged, according to the Centers for Disease Control and Prevention. Over time, this condition can lead to kidney failure, heart attack and stroke. But as many as 90% of people … Read more

Groundbreaking Renal Denervation Protects Kidney Function in Resistant Hypertension and Diabetes

Archyde Breakthrough Procedure Offers New Hope for kidney Disease Patients Table of Contents 1. Breakthrough Procedure Offers New Hope for kidney Disease Patients 2. Understanding distal Renal Denervation 3. The Critical… You can read the full story here: Groundbreaking Renal Denervation Protects Kidney Function in Resistant Hypertension and Diabetes. Source link

Obesity’s role in shared genetic risks of chronic diseases

A sweeping genetic analysis reveals when obesity is the common thread linking chronic diseases, and when other biology is to blame. Study: Genetics identifies obesity as a shared risk factor for co-occurring multiple long-term conditions. Image credit: MaskaRad/Shutterstock.com A recent study in Communications Medicine completed a genetic analysis to determine whether body mass index (BMI) affects … Read more

Reducing sodium in common foods could prevent heart disease and stroke

Lowering sodium in packaged and prepared foods could significantly improve cardiovascular health and prevent many cases of heart disease, stroke and deaths in the general population in France and the U.K., according to two new research studies published today in Hypertension, an American Heart Association journal. Consuming too much sodium is a major risk factor for hypertension, … Read more

Improving survival in people with severe psychiatric disorders

An expert editorial suggests that widely used diabetes and obesity drugs may help close the long-standing mortality gap faced by people with serious mental illnesses by tackling cardiovascular risk and metabolic disease head-on. Editorial: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have potential to transform health outcomes for persons with bipolar disorder, schizophrenia, major depressive disorder … Read more

Scientists discover why patients with chronic kidney disease die of heart problems

Scientists have discovered an answer to the longstanding mystery of why more than half of patients with chronic kidney disease ultimately die of cardiovascular problems: Their kidneys produce a substance that poisons the heart. The researchers, at UVA Health and Mount Sinai, say the discovery could let doctors identify people at risk and develop new … Read more

Majority of older adults in Ireland have poorly controlled high blood pressure

High blood pressure becomes more common after age 40years yet new research from The Irish Longitudinal Study on Ageing (TILDA) at Trinity College Dublin shows that many people in Ireland with hypertension are still not optimally diagnosed or treated based on European Gudelines. The study is published in the international journal Open Heart. High blood pressure … Read more

Early smoking and its impact on cardio-cerebrovascular diseases in patients with chronic kidney disease: a nationwide population-based study | BMC Public Health

In the present nationwide retrospective cohort study of patients with CKD, we investigated the associations between smoking initiation age, smoking intensity (pack-years), and the risks of CCVDs and all-cause mortality. The results indicated that both early smoking initiation and higher cumulative smoking exposure were independently associated with worse health outcomes in CKD patients. This study … Read more