Shiitake-based supplement may help prevent liver damage progression

Early use of AHCC during hepatitis stages shows potential to reduce the risk of cirrhosis, according to new research

Growing Shiitake Mushrooms
Study: AHCC inhibited hepatic stellate cells activation by regulation of cytoglobin induction via TLR2-SAPK/JNK pathway and collagen production via TLR4-NF-κβ pathway. Image Credit: guys_who_shoot/Shutterstock.com

A recent report in Gastrointestinal and Liver Physiology presents the effect of a functional food called active hexose correlated compound (AHCC) on liver fibrosis.

What is AHCC?

A Japanese firm, Amino Up Co., Ltd., produces a standardized extract of the mycelia of the cultured mushroom Lentinula edodes. AHCC has shown the ability to increase dendritic cell numbers in the blood, enhance virus elimination, increase influenza antibody titers post-vaccination, and reduce…

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