New research shows that in patients with psoriasis, even though their skin responds well to treatment with biologics, inflammation can linger, leading to broader health implications such as obesity and cardiovascular and fatty liver disease. The findings of the study in the Journal of Investigative Dermatology (JID), published by Elsevier, could lead to more targeted and effective treatments that address the systemic aspects of psoriasis, beyond just the skin.
Systemic chronic inflammation has been implicated in several diseases that collectively represent the leading causes of disability and mortality worldwide, such as cardiovascular disease, cancer, diabetes mellitus, chronic kidney disease, non-alcoholic fatty liver disease, and autoimmune and neurodegenerative disorders. Psoriasis, with its…