New algorithm enables precise subtyping of metabolic liver disease

Metabolic-associated steatotic liver disease (MASLD) is a clinically heterogeneous condition with highly variable outcomes affecting more than 30% individuals globally. The disease is conventionally staged by histological progression, ranging from simple steatosis to metabolic dysfunction-associated steatohepatitis (MASH) and ultimately fibrosis or cirrhosis. Beyond liver-related outcomes, MASLD significantly elevates the risk of extrahepatic complications, including cardiovascular … Read more

Tailored prediabetes treatment may better prevent Type 2 diabetes

A one-size-fits-all approach to prediabetes treatment may miss the opportunity to implement an early, more intensive, tailored prevention approach for those with the highest risk of developing Type 2 diabetes, according to preliminary research presented at the American Heart Association’s EPI|Lifestyle Scientific Sessions 2026. The meeting is in Boston, March 17-20, 2026, and offers the latest science … Read more

€300 million dialysis costs show need for earlier kidney disease interventions – charity

Around 5,500 patients are living with end-stage kidney disease in Ireland, with 2,647 receiving dialysis treatment The high cost of dialysis treatment in Ireland shows the importance of early detection and intervention when it comes to kidney disease, the CEO of the Irish Kidney Association (IKA) has said. Carol Moore, CEO, Irish Kidney Association Carol … Read more

New strategy to fight chronic kidney inflammation

Mayo Clinic researchers have identified a drug-and-supplement combination therapy that is capable of reducing the harmful effects of senescent cells – also known as “zombie cells” – in diabetic kidney disease. In eBioMedicine, a publication of The Lancet, the team reported that the combination of the cancer drug dasatanib and a naturally occurring substance known as quercetin decreased inflammation … Read more

Combination therapy can reduce harmful effects of senescent cells in diabetic kidney disease

Mayo Clinic researchers have identified a drug-and-supplement combination therapy that is capable of reducing the harmful effects of senescent cells – also known as “zombie cells” – in diabetic kidney disease. In eBioMedicine, a publication of The Lancet, the team reported that the combination of the cancer drug dasatanib and a naturally occurring substance known as quercetin decreased inflammation … Read more

How are GLP-1 drugs reshaping treatment for obesity, diabetes, and heart disease?

A sweeping Lancet review reveals how modern incretin-based drugs are reshaping treatment for obesity and diabetes, delivering powerful weight loss while simultaneously protecting the heart, kidneys, and metabolic health. Review: GLP-1 receptor agonists and next-generation incretin-based medications: metabolic, cardiovascular, and renal benefits. Image Credit: Gecko Studio / Shutterstock In a recent review published in The … Read more

Heart attack deaths increase in young adults, especially women

A new study found that heart attack deaths were up among younger adults with women more likely than men to die after a first heart attack. According to new research published today in a Go Red for Women spotlight issue of the Journal of the American Heart Association, an open access, peer-reviewed journal of the American … Read more

Prior COVID infection increases kidney disease risk

Approximately one in seven adults in the United States has kidney disease, where the organs responsible for filtering waste and excess water from the blood are damaged, according to the Centers for Disease Control and Prevention. Over time, this condition can lead to kidney failure, heart attack and stroke. But as many as 90% of people … Read more

High-fat ketogenic diet improves exercise response in diabetic mice

To be healthy, conventional wisdom tells us to exercise and limit fatty foods. Exercise helps us lose weight and build muscle. It makes our hearts stronger and boosts how we take in and use oxygen for energy – one of the strongest predictors of health and longevity. But people with high blood sugar often don’t … Read more