Mayo Clinic research identified a powerful new way to improve the prediction of a patient’s long-term cardiovascular disease risk by enhancing a routinely performed imaging test with artificial intelligence (AI). Heart disease develops over time and remains the leading cause of death worldwide, so identifying risk early is critical to preventing heart attack, stroke and other serious outcomes. … Read more
Tirzepatide is one of the drugs that has revolutionized the treatment of obesity and other conditions such as diabetes in recent years. Despite its clinical success, its precise molecular and cellular mechanisms are still not fully understood. A study in mice shows that the drug has a direct impact on improving metabolism by activating brown … Read more
Many people may have a dim view of their fat tissue, yet scientists have come to recognize adipose as a necessary and metabolically active organ, carrying out many vital functions within the body. In the case of obesity, too much fat can contribute to conditions such as diabetes and heart disease. Intriguingly, for people with … Read more
Obesity causes hypertension. Hypertension causes cardiovascular disease. And cardiovascular disease is the leading cause of death worldwide. While the link between fat and high blood pressure is clearly central to this deadly chain, its biological basis long remained unclear. What is it about fat that impacts vascular function and blood pressure control? Now, a new … Read more
New research shows that in patients with psoriasis, even though their skin responds well to treatment with biologics, inflammation can linger, leading to broader health implications such as obesity and cardiovascular and fatty liver disease. The findings of the study in the Journal of Investigative Dermatology (JID), published by Elsevier, could lead to more targeted … Read more
The prototype of a new machine that can detect tumors in women with dense breast tissue has been developed by researchers from UCL, Newcastle Hospitals and Newcastle University, in partnership with international technology group Kromek. All breasts are composed of adipose (fatty) and fibroglandular (dense) tissue. Up to 40% of women have dense breasts containing … Read more
A new study uncovers how endothelial cells contribute to insulin resistance in obesity-associated diabetes, highlighting adrenomedullin as a potential therapeutic target. Study: Endothelial insulin resistance induced by adrenomedullin mediates obesity-associated diabetes. Image Credit: Kateryna Kon / Shutterstock.com A recent study published in Science investigates the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes. What … Read more
Graft-versus-host disease (GVHD) is a common and severe complication that occurs after stem cell transplantation, where the donor’s immune cells attack the recipient’s tissues. Ocular manifestation of GVHD is among the most challenging to treat, often leading to chronic inflammation and corneal tissue damage, which can result in loss of vision. Conventional treatments, including corticosteroids, … Read more
Here is the content you requested: Decoding fat tissue | EurekAlert! New research from the University of Delaware aims to tackle the issue by investigating obesity at the gene level.Principal investigator Ibra Fancher, assistant professor of kinesiology and applied physiology in UD’s College of Health sciences, discovered significant differences in gene expression in adipose tissue, … Read more
As many as 40% of Americans are obese, putting them at an increased risk for high blood pressure, diabetes, stroke, heart disease and certain cancers, according to the CDC. New research from the University of Delaware aims to tackle the issue by investigating obesity at the gene level. Principal investigator Ibra Fancher, assistant professor of kinesiology and … Read more