Imaging Techniques

Lysosomal storage of drugs may influence cancer treatment outcomes

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One of oncology’s biggest challenges is that the same treatment can work well for some patients but fail completely in others. A study published in Nature Communications, from a multi-disciplinary team led by Dr Louise Fets at the LMS, has mapped the distribution of a type of targeted treatments, known as PARP inhibitors, using advanced imaging techniques and patient ovarian tumour samples. The research reveals that build up of these drugs in lysosomes – small compartments inside cells that normally act as “recycling centres” – can trap and … Read more

Accurate determination of the 3D atomic structure of amorphous materials

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Nomura, K. et al. Room-temperature fabrication of transparent flexible thin-film transistors using amorphous oxide semiconductors. Nature 432, 488–492 (2004). Article  ADS  CAS  PubMed  Google Scholar  Carlson, D. E. & Wronski, C. R. Amorphous silicon solar cell. Appl. Phys. Lett. 28, 671–673 (1976). Article  ADS  CAS  Google Scholar  Wuttig, M., Bhaskaran, H. & Taubner, T. Phase-change … Read more

New 2026 guideline expands access to advanced acute ischemic stroke care

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Expanded eligibility for advanced stroke therapies and new recommendations for diagnosing and treating stroke in children and adults are among the major updates in the new 2026 Guideline for the Early Management of Patients With Acute Ischemic Stroke from the American Stroke Association, a division of the American Heart Association, published today in the Association’s flagship journal Stroke. … Read more

Digital CRISPR-based diagnostics for quantification of Candida auris and resistance mutations

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WHO Fungal Priority Pathogens List to Guide Research, Development and Public Health Action (World Health Organization, 2022). Fisher, M. C. et al. Tackling the emerging threat of antifungal resistance to human health. Nat. Rev. Microbiol. 20, 557–571 (2022). Article  PubMed  PubMed Central  CAS  Google Scholar  Antibiotic Resistance Threats in the United States 2019 (CDC, 2019). … Read more

Early brain wiring holds clues to infant emotional development

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In a comprehensive Genomic Press research article, scientists have uncovered remarkable insights into how the earliest brain connections shape infant emotional development, potentially offering new ways to identify children at risk for future behavioral and emotional challenges. The groundbreaking study, led by Dr. Yicheng Zhang and Dr. Mary L. Phillips at the University of Pittsburgh … Read more

Enhancing early breast cancer diagnosis through modern imaging technologies

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Breast cancer remains a leading cause of cancer-related mortality globally, underscoring the critical need for early detection to improve survival rates and reduce treatment invasiveness. This review synthesizes advancements in imaging technologies that enhance early diagnosis, focusing on their clinical applications, limitations, and future potential. Introduction Breast cancer accounts for 25% of cancer cases in … Read more

MRI & Eating Disorders: Why Young Women Are More Vulnerable

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## Decoding the Female Brain: New MRI Insights into Eating Disorders and Weight Regulation Recent advancements in magnetic resonance imaging (MRI) are providing unprecedented clarity into the neurological factors underlying eating disorders and obesity, specifically in young women. These breakthroughs are moving beyond conventional understandings and opening doors to more targeted and effective interventions. <span … Read more

MRI scans reveal why young women face higher risk for eating disorders

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Breakthrough MRI scans reveal hidden hypothalamic changes in young women, shedding light on the biological roots of anorexia and obesity, and paving the way for targeted treatments. Study: Unraveling neural underpinnings of eating disorders in the female brain: Insights from high-field magnetic resonance imaging. Image Credit: Suppakjj1017 / Shutterstock.com A recent editorial feature published in the American … Read more

Research reveals how dendrites connect memories in the brain

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If you’ve ever noticed how memories from the same day seem connected while events from weeks apart feel separate, a new study reveals the reason: Our brains physically link memories that occur close in time not in the cell bodies of neurons, but rather in their spiny extensions called dendrites. This discovery stems from studies … Read more