clinical research

Home HPV Self-Sampling Kits Show Promise for Closing Cervical Screening Gap in Disabled Women

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A new study from the University of Sheffield suggests that at-home human papillomavirus (HPV) self-sampling kits could help address persistent gaps in cervical cancer screening among physically disabled women, a population that faces disproportionate barriers to traditional in-person screenings. The National Institute for Health and Care Research-funded study, published in the Journal of Medical Screening, … Read more

Opening clinical trials to pregnant women

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Pregnant and breastfeeding women have historically been excluded from medical research, resulting in substantial gaps in evidence on the safety and efficacy of medicines and vaccines. Analysis led by the Global Observatory on Health Research and Development of all clinical trials in the International Clinical Trials Registry Platform (ICTRP) reveals that just 4% of clinical trials … Read more

Novel antibody blocks Epstein-Barr virus, curing follicular lymphoma — and a plan to reduce cancer in Washington state

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SEATTLE – March 4, 2026 – Below are summaries of recent Fred Hutch Cancer Center research findings, patient stories and other news. March is the awareness month for colorectal cancer and multiple myeloma. If you’re interested in speaking to experts, contact [email protected] to schedule interviews. Infectious disease research Scientists develop first-of-its-kind antibody to block Epstein-Barr … Read more

Nutrition Priorities for GLP-1 Use in Obesity

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TOPLINE: Four clinical organizations jointly released a clinical advisory with evidence-based nutrition and lifestyle interventions to enhance glucagon-like peptide 1 (GLP-1) treatment outcomes for obesity. METHODOLOGY: An expert group comprised of multiple clinical and research disciplines assessed the literature to identify pragmatic priorities for nutrition and other lifestyle interventions relevant to GLP-1 treatment for obesity. … Read more

Herpesvirus-associated diseases: biomarkers and advancements in clinical research | Virology Journal

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Connolly SA, Jardetzky TS, Longnecker R. The structural basis of herpesvirus entry. Nat Rev Microbiol. 2021;19(2):110–21. PubMed  Google Scholar  Gilden DH, Mahalingam R, Cohrs RJ, Tyler KL. Herpesvirus infections of the nervous system. Nat Clin Pract Neurol. 2007;3(2):82–94. PubMed  Google Scholar  Lan K, Luo MH. Herpesviruses: epidemiology, pathogenesis, and interventions. Virol Sin. 2017;32(5):347–8. PubMed  PubMed … Read more

Smartphone Monitoring Cuts BP Post-ED Discharge

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TOPLINE:  In a study, patients who received a team-based intervention involving education and mobile health support in the emergency department (ED) had greater reduction in systolic blood pressure (SBP) at 6 months than those who received standard discharge care. METHODOLOGY: A randomized clinical trial enrolled 574 adult patients (mean age, 51.1 years) with elevated BP … Read more

New Drug for Acute Schizophrenia Effective in Phase 2 Study

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LOS ANGELES — The novel phosphodiesterase 10A (PDE10A) inhibitor known as CPL’36 (Celon Pharma) is effective and generally safe in acute exacerbations of schizophrenia, new research suggested. In a phase 2 trial of 189 patients with acute schizophrenia, compared with the placebo group, the groups receiving CPL’36 20 or 40 mg once daily both met … Read more

New Genetic Test Could Diagnose Brain Tumours in 2 Hours

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Researchers at the University of Nottingham have developed a new genetic test that can diagnose brain tumours in as little as 2 hours The test, called ROBIN, uses PromethION nanopore sequencing to deliver rapid methylome classification. The researchers said results could be available intraoperatively, allowing clinicians to make faster, more informed decisions. The same assay … Read more

New ‘Real World’ Data on Lecanemab Side Effects

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Patients with early Alzheimer’s disease (AD) who initiated lecanemab treatment at a specialty memory clinic showed an expected and manageable side-effect profile, new research showed. “The findings are very reassuring,” Barbara Joy Snider, MD, PhD, professor of neurology, and director of the Memory Diagnostic Center and Knight ADRC Clinical Trials Unit, Washington University School of … Read more

No Barrett’s Survival Benefit With Regular Surveillance

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SAN DIEGO—Gastroenterologists have debated the best course of action for patients with Barrett’s esophagus for decades. Which is better for detecting early malignancy and preventing progression to esophageal adenocarcinoma (EAC) — surveillance endoscopy at regular intervals or only when symptoms occur? Does one offer a better chance of survival than the other? Now, researchers who … Read more