TOPLINE: Patients with Sjögren disease (SjD) had a 68% higher risk for overall malignancy than the general population, with hematologic malignancies contributing more to this elevated risk than solid tumors. Cancer accounted for 23.8% of deaths, with older age at diagnosis, smoking, lymphadenopathy, splenomegaly, and cryoglobulinemia identified as key predictors. METHODOLOGY: Researchers conducted a prospective … Read more
In this study, we found that the clinical and CT findings of ATBL can differ between patients with hematogenous dissemination and those with non-hematogenous dissemination. These findings aid in the early diagnosis of ATBL. Our results showed a significant tendency for non-hematogenous dissemination in males and younger individuals. This may be due to more frequent … Read more
Apr 10 2025 Large granular lymphocytic leukemias (LGLLs) are a heterogeneous group of rare chronic lymphoproliferative disorders characterized by the clonal proliferation of cytotoxic lymphocytes. Among them, T-cell LGLL (T-LGLL) and NK-cell LGLL (NK-LGLL) are the most prominent. Due to overlapping morphological, clinical, and immunophenotypic characteristics, distinguishing these disorders from related entities such as T-prolymphocytic … Read more