Updated EULAR recommendations guide treatment decisions for rheumatoid arthritis

First published in 2010, the EULAR recommendations for the management of RA, the most frequent inflammatory rheumatic disease, have been relied upon by healthcare professionals and organisations worldwide to offer an up-to-date and robust analysis of the effectiveness and practical use of available DMARDs – from conventional agents such as methotrexate to biologics and Janus … Read more

Targeted PET/CT tracer improves early prediction of treatment response in rheumatoid arthritis patients

A new targeted PET/CT tracer can detect treatment response in rheumatoid arthritis patients in as little as four weeks, and potentially even at the start of treatment, according to new research published in The Journal of Nuclear Medicine. Compared to the three to six months currently required to establish treatment efficacy, this new imaging technique could … Read more

Early treatment delays rheumatoid arthritis onset in high-risk individuals

Treating people who are at high risk of rheumatoid arthritis (RA) can delay the onset of the disease for several years, with benefits also continuing well after treatment has stopped. The trial showed that one year of treatment with the drug abatacept, a biologic therapy that targets immune cell activation, reduced progression to rheumatoid arthritis … Read more

Increased Incidence but Lower Mortality From RA Seen Over Last 3 Decades

While rheumatoid arthritis (RA)–related mortality seems to be dropping, the prevalence of disease continues to increase across the globe, a new analysis found. The analysis highlights the need for research and health care policies addressing certain risk factors, according to the authors.1 Published in Scientific Reports, the analysis showed increasing numbers of RA over the … Read more

Researchers establish a new golden standard for human lactation studies

Women who choose to stop treatment during pregnancy and breastfeeding are putting their health at risk, and have to weigh their desire to have children and breastfeed against a risk that we know very little about. In two ongoing clinical trials, researchers establish a new standard for human lactation studies that includes sampling of breast … Read more

The characteristics of peripheral blood lymphocyte main subsets in rheumatoid arthritis patients concurrent with hepatitis b virus infection: a retrospective cohort study | BMC Infectious Diseases

Study population Patients (n = 298) who fulfilled the 1987 revised criteria of the American College of Rheumatology (ACR) or the 2010 ACR/European League Against Rheumatism criteria for RA classification were retrospectively recruited from the Zhejiang University School of Medicine-Affiliated Jinhua Hospital between March 2022 and March 2023. Patients with RA (n = 43) who had hepatitis … Read more

Refining the diagnosis of large granular lymphocytic leukemias and their mimics

Apr 10 2025 Large granular lymphocytic leukemias (LGLLs) are a heterogeneous group of rare chronic lymphoproliferative disorders characterized by the clonal proliferation of cytotoxic lymphocytes. Among them, T-cell LGLL (T-LGLL) and NK-cell LGLL (NK-LGLL) are the most prominent. Due to overlapping morphological, clinical, and immunophenotypic characteristics, distinguishing these disorders from related entities such as T-prolymphocytic … Read more

Annual COVID-19 boosters crucial for immunocompromised individuals

New research findings provide solid evidence that annual COVID-19 vaccine booster doses continue to be advisable for certain immunocompromised people, researchers at McGill University say. The researchers looked at how often people with immune-mediated inflammatory diseases (IMIDs) got COVID-19 despite having received at least three doses of an mRNA COVID-19 vaccine. IMIDs – including rheumatoid … Read more

New research paves the way for non-hormonal endometriosis treatments

Roughly 200 million women around the world suffer from endometriosis, a condition that causes tissue from the lining of the uterus to grow in places outside of the uterus. The condition can be exceptionally painful and contributes to infertility. Endometriosis is as common as Type 2 diabetes, rheumatoid arthritis and migraines in the U.S., although … Read more