Immunophenotyping

Refining the diagnosis of large granular lymphocytic leukemias and their mimics

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Apr 10 2025 Large granular lymphocytic leukemias (LGLLs) are a heterogeneous group of rare chronic lymphoproliferative disorders characterized by the clonal proliferation of cytotoxic lymphocytes. Among them, T-cell LGLL (T-LGLL) and NK-cell LGLL (NK-LGLL) are the most prominent. Due to overlapping morphological, clinical, and immunophenotypic characteristics, distinguishing these disorders from related entities such as T-prolymphocytic … Read more

Harnessing AI to combat rheumatoid arthritis

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Fan Zhang, PhD, sees artificial intelligence as a pathway to finding an effective way to combat an intractable enemy: rheumatoid arthritis. Zhang is an assistant professor in the University of Colorado Department of Medicine’s Division of Rheumatology and also is affiliated with the Department of Biomedical Informatics on the CU Anschutz Medical Campus. She recently … Read more

Immune system changes may predict antipsychotic resistance in schizophrenia Scientis…

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Researchers from the National Healthcare Group (NHG)’s Institute of Mental Health (IMH) and Agency for Science, Technology and Research (A*STAR) have made strides in understanding the connection between the immune system and resistance to antipsychotic medications in schizophrenia, using changes in immune cell populations to predict potential treatment resistance and initiate the most appropriate treatment … Read more