meta-analysis

Unfavorable outcomes and their predictors in patients treated for perforated peptic ulcer disease in Ethiopia: systematic review and meta-analysis | BMC Gastroenterology

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Search results The initial search yielded a total of 223 articles from various sources. After removing 20 duplicate articles, 203 unique articles remained. Subsequently, 189 articles that were deemed irrelevant for this review were excluded, leaving 14 articles for further analysis. Out of these, 3 articles were not available in full-text and could not be … Read more

Radiotherapy for Prostate Cancer: What Approach Works Best?

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TOPLINE: Moderately hypofractionated radiotherapy, both isodose and dose-escalated, led to progression-free survival outcomes similar to that achieved with conventionally fractionated radiotherapy in patients with prostate cancer, but the dose-escalated regimen came with an increased risk for toxicities compared with the conventional approach, according to findings from a recent meta-analysis. METHODOLOGY: Moderately hypofractionated radiotherapy is now … Read more

GLP-1 Receptor Agonists and Suicide Risk: What the Evidence Shows

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Archyde Do Weight Loss Drugs Like Ozempic Increase Suicide Risk? New Study Offers Reassuring Data Table of Contents 1. Do Weight Loss Drugs Like Ozempic Increase Suicide Risk? New Study Offers Reassuring Data 2. Key Findings: GLP-1 RAs and Suicidality 3. Delving into the Methodology 4. Beyond the Numbers: A Nuanced Perspective 5. Putting the … Read more

GLP-1 RAs Unlikely to Increase Suicide Risk

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TOPLINE: A meta-analysis of randomized controlled trials involving over 59,000 patients with diabetes or obesity showed no statistically significant difference in the risk for suicide between those treated with glucagon-like peptide 1 receptor agonists (GLP-1 RAs) and placebo. METHODOLOGY: Initial reports of increased suicidality in GLP-1 RA users compared with the general population raised concerns … Read more

Discontinuing Oxytocin in Active Labor Reduces Cesarean Risk

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TOPLINE: Discontinuing oxytocin during active labor was associated with a 20% lower risk for cesarean delivery and reduced the risk for uterine tachysystole and non-reassuring fetal heart rate tracings. The approach extends labor duration by approximately 30 minutes but shows potential benefits for delivery outcomes. METHODOLOGY: Researchers conducted a systematic review and meta-analysis of 15 … Read more

Vaccinations Show No Link to Risk for Rheumatoid Arthritis

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TOPLINE: A meta-analysis of 16 observational studies found no significant association between vaccination exposure and risk for rheumatoid arthritis (RA). Short-term follow-up data (< 1 year) suggested that vaccines may protect against RA.  METHODOLOGY: Researchers assessed the association between vaccinations and RA incidence and relapse by conducting an updated systematic review and meta-analysis of 16 … Read more

Diagnostic Imaging's Weekly Scan: March 9 — March 15 – Diagnostic Imaging

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Diagnostic Imaging’s Weekly Scan: March 9 — March 15  Diagnostic Imaging Denoised ultra-low dose CT offers safe pneumonia diagnosis for immunocompromised patients  News-Medical.Net Pneumonia diagnosis: deep learning takes the grain out of ultra-low dose CT  healthcare-in-europe.com Source link

Associations of the gut, cervical, and vaginal microbiota with cervical cancer: a systematic review and meta-analysis | BMC Women’s Health

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Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer statistics 2020: GLOBOCAN estimates of incidence and Mortality Worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–49. Article  PubMed  Google Scholar  Crosbie EJ, Einstein MH, Franceschi S, Kitchener HC. Human papillomavirus and cervical cancer. Lancet. 2013;382(9895):889–99. … Read more

Short Sleep Is Linked to an Increased Risk for Hypertension

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TOPLINE: A nighttime sleep duration less than 7 hours was associated with an increased risk for hypertension, especially in women. No significant association was found between a sleep duration more than 8 hours and the risk for hypertension. METHODOLOGY: Researchers conducted a systematic review and meta-analysis of 23 prospective cohort studies to explore the association … Read more

Systematic review and meta-analysis of colistin heteroresistance in Klebsiella pneumoniae isolates | BMC Infectious Diseases

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Jayol A, Nordmann P, Brink A, Poirel L. Heteroresistance to colistin in Klebsiella pneumoniae associated with alterations in the PhoPQ regulatory system. Antimicrob Agents Chemother. 2015;59(5):2780–4. Article  PubMed  PubMed Central  Google Scholar  Sato T, Wada T, Nishijima S, Fukushima Y, Nakajima C, Suzuki Y, et al. Emergence of the novel aminoglycoside acetyltransferase variant aac (6′)-Ib-D179Y … Read more