nonalcoholic fatty liver disease

Relative fat mass and risk of metabolic dysfunction associated steatotic liver disease and severe hepatic steatosis in U.S. adults: analysis of NHANES 2017–2020 data | BMC Gastroenterology

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In this study, we found that elevated RFM was significantly associated with an increased odds of both MASLD and SHS after adjusting for potential confounders. Moreover, there was a nonlinear relationship between RFM and the prevalence of MASLD and SHS, with a threshold of 41.96 for MASLD risk and 40.42 for SHS risk. In addition, … Read more

Fatty Liver Disease Nearly Doubles Mortality Risk

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TOPLINE: Patients with metabolic dysfunction-associated steatotic liver disease (MASLD) face significantly higher risks of dying from nearly all major causes, with the most pronounced relative risks observed for hepatocellular carcinoma (HCC) and liver-related deaths, and the highest absolute mortality rates for non-HCC cancer and cardiovascular disease. METHODOLOGY: MASLD is the most common chronic liver disease … Read more

A negative correlation of low estimated glucose disposal rate with significant liver fibrosis in adults with NAFLD and obesity: results from NHANES 2017–2020 | BMC Gastroenterology

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Characteristics of participants The data from 1585 individuals were analyzed, including 224 participants with significant fibrosis and 1361 with nonsignificant fibrosis (Table 1). Individuals with significant fibrosis were older and had higher levels of various biomarkers, including CAP, BMI, ALT, AST, GGT, UA, CRP, and WBC count (all P < 0.01) and lower eGDR and platelet count (all … Read more

Rite of Passage or Road to Early Liver Damage?

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As a transplant hepatologist in Los Angeles, Brian Lee, MD, MAS, has seen his share of alcoholics with advanced liver disease, people who have spent decades drinking their body toward an early death. In recent years, however, the demographic of these patients has shifted in a particularly worrisome direction. More than ever, young adults and … Read more

A Common Pancreatic Condition That Few Have Heard Of

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The most common pathology affecting the pancreas is excess intra-pancreatic fat deposition (IPFD), often called fatty pancreas disease (FPD) — a disorder experienced by roughly one fifth of the world’s population. Although it is more common than type 2 diabetes, pancreatitis, and pancreatic cancer combined, it has remained relatively obscure. By contrast, fatty liver — … Read more

Bariatric Surgery Lowers Risk for Liver Complications in MASH

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Among patients with obesity and compensated cirrhosis, bariatric surgery may significantly lower the risk of developing serious liver disease complications, according to a recent study by Cleveland Clinic researchers. Compared with patients who received medical therapy alone, those who underwent bariatric surgery had a 72% lower risk of developing serious complications of liver disease and … Read more

ADA Focus on Diabetes Self-Management, ‘Exceedingly Useful’

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This transcript has been edited for clarity.  Welcome to the second video on the American Diabetes Association’s Standards of Care in Diabetes—2025.  We’re starting with Section 5, “ Facilitating Positive Health Behaviors and Well-Being to Improve Health Outcomes.”  The section emphasizes the notion that people really need to be referred for diabetes self-management education and … Read more