TOPLINE: Four clinical organizations jointly released a clinical advisory with evidence-based nutrition and lifestyle interventions to enhance glucagon-like peptide 1 (GLP-1) treatment outcomes for obesity. METHODOLOGY: An expert group comprised of multiple clinical and research disciplines assessed the literature to identify pragmatic priorities for nutrition and other lifestyle interventions relevant to GLP-1 treatment for obesity. … Read more
TOPLINE: In a study, patients who received a team-based intervention involving education and mobile health support in the emergency department (ED) had greater reduction in systolic blood pressure (SBP) at 6 months than those who received standard discharge care. METHODOLOGY: A randomized clinical trial enrolled 574 adult patients (mean age, 51.1 years) with elevated BP … Read more
Researchers at the University of Nottingham have developed a new genetic test that can diagnose brain tumours in as little as 2 hours The test, called ROBIN, uses PromethION nanopore sequencing to deliver rapid methylome classification. The researchers said results could be available intraoperatively, allowing clinicians to make faster, more informed decisions. The same assay … Read more
Patients with early Alzheimer’s disease (AD) who initiated lecanemab treatment at a specialty memory clinic showed an expected and manageable side-effect profile, new research showed. “The findings are very reassuring,” Barbara Joy Snider, MD, PhD, professor of neurology, and director of the Memory Diagnostic Center and Knight ADRC Clinical Trials Unit, Washington University School of … Read more
SAN DIEGO—Gastroenterologists have debated the best course of action for patients with Barrett’s esophagus for decades. Which is better for detecting early malignancy and preventing progression to esophageal adenocarcinoma (EAC) — surveillance endoscopy at regular intervals or only when symptoms occur? Does one offer a better chance of survival than the other? Now, researchers who … Read more
For the first time, the number of Americans living with Alzheimer’s disease (AD) has surpassed 7 million, according to the Alzheimer’s Disease Facts and Figures report released this week. An estimated 7.2 million people aged 65 years or older are now living with AD, up from an estimated 6.9 million in the 2024 report. Three … Read more
TOPLINE: In patients with type 2 diabetes (T2D), combination therapy with glucagon-like peptide 1 receptor agonists (GLP-1 RAs) and thiazolidinediones was associated with a reduced risk for all-cause mortality, cardiovascular mortality, and major adverse cardiovascular events (MACEs) compared with those who used none or one of these therapies. METHODOLOGY: For people with T2D, the potential … Read more
A new social media trend is making headlines: Methylene blue is being touted as a cognitive booster and antiaging miracle. Influencers such as Ben Greenfield are promoting the use of this chemical to enhance brain performance, strengthen the immune system, and even prevent cancer without providing scientific evidence. Researchers have warned that methylene blue can … Read more
The use of smoking cessation medications during the first trimester of pregnancy posed no greater risk for major congenital malformations (MCMs) in infants than smoking, based on a meta-analysis of approximately 400,000 infants. “Maternal smoking during pregnancy is the leading cause of harms to both mother and baby, contributing to outcomes such as preterm birth, … Read more
A teaspoon of salt. This is the amount of sodium that US dietary guidelines recommend that people consume a day. Yet salt consumption is often higher than the recommended amount. The progression of evidence about the effect of salt on cardiovascular health has marched forward from studies showing a reduction in consumption associated with lower … Read more