Researchers have discovered that mutations in the FOXJ3 gene act as a “master switch” failure, disrupting how the brain builds its layers and leading to FCD, a primary cause of drug-resistant epilepsy. The study reveals how FOXJ3 controls the formation of brain cortical layers during brain development by regulating the PTEN–mTOR signaling pathway. The PTEN-mTOR … Read more
Early hydrocortisone treatment of extremely premature babies increases their chances of survival without lung disease, according to a study led by Linköping University. The study also shows that the treatment is safe to give. The results are published in JAMA Network Open. More than half of babies born extremely prematurely – before 28 weeks of … Read more
Researchers have developed and internally validated a simple score using clinical factors that can help estimate the likelihood of advanced colorectal neoplasia in adults younger than age 45 years. While colorectal cancer (CRC) incidence has declined overall due to screening, early-onset CRC is on the rise, particularly in individuals younger than 45 years — an … Read more
The American College of Gastroenterology (ACG) has issued its first clinical practice guideline on the diagnosis and management of gastric premalignant conditions (GPMCs) including atrophic gastritis, gastric intestinal metaplasia, dysplasia, and certain gastric epithelial polyps, all of which have an increased risk of progressing to gastric cancer. The guideline was published online on March 12 … Read more
More than 50 million people worldwide live with epilepsy, with approximately half of them being children. For about one-third of these patients, medications do not control their seizures, leaving surgery as the only viable option for seizure relief. Seizures in 60 percent of these drug-resistant cases start in one part of the brain, making surgical … Read more
The disparities between men and women in prevalence, risk factors and symptoms of peripheral vascular disease (PVD) have a profound impact on prevention, diagnosis, treatment and outcomes for women, according to a new American Heart Association scientific statement published today in the Association’s flagship, peer-reviewed journal Circulation. “Peripheral vascular disease is often under-recognized and understudied in women,” … Read more
Can AI unmask Hidden Epilepsy Lesions? Table of Contents Can AI unmask Hidden Epilepsy Lesions? AI Algorithm Shows Promise in Detecting Hidden Epilepsy Lesions AI Could Revolutionize Epilepsy Diagnosis and Treatment Can AI Unmask Hidden Epilepsy Lesions? New AI Algorithm Shows Promise in Detecting Subtle Brain Abnormalities How the AI Algorithm Works Open-Source and Collaborative … Read more
Archyde Understanding lung Health in Former Preemies: Paving the Way for Future Research research on the long-term lung health of premature infants is still in its early stages. While we certainly know prematurity can increase the risk of respiratory problems, there’s a lack of comprehensive data tracking how lung function evolves in these individuals as … Read more
Infants born preterm remain vulnerable to numerous health complications, such as respiratory distress syndrome, chronic lung disease, and pulmonary dysfunction. Moreover, extremely low gestational age neonates (ELGANs), or babies born more than 3 months before the expected date of birth ( Existing methods to evaluate lung function such as spirometry are limited by the … Read more