Electrical Stimulation stimulation restores movement and sensory feedback after severe spinal injury

The effects of spinal cord injuries are complex and multifaceted. People lose not only the ability to control the movement of their limbs, but also the ability to receive sensory feedback from them. Both are critical to generate the coordinated movement involved in walking. Now, a team of researchers from Brown University, Rhode Island Hospital, … Read more

Targeting STING Pathway Triggers Cytotoxic and Immune Responses Against Meningioma

Mark Youngblood, MD, PhD, a resident physician in neurological surgery and lead author of the study. Northwestern Medicine scientists have discovered a potent immunotherapy approach for treating meningiomas, the most common type of primary brain tumor, according to a recent study published in Nature Communications. More than 39,000 Americans are diagnosed with meningioma each year, … Read more

Study identifies brain region driving one-shot visual learning

Despite decades of research, the mechanisms behind fast flashes of insight that change how a person perceives their world, termed “one-shot learning,” have remained unknown. A mysterious type of one-shot learning is perceptual learning, in which seeing something once dramatically alters our ability to recognize it again. A new study, led by researchers at NYU … Read more

Eosinophils suppress tumor growth and recurrence in chordoma

Chordoma is a rare tumor characterized by poor prognosis, limited therapeutic options, and a high rate of recurrence. Despite advances in oncology, effective treatments for chordoma remain limited. Resistance to conventional radiotherapy and chemotherapy restricts therapeutic options, and surgical treatment is often challenging due to the tumor’s proximity to critical anatomical structures. Consequently, identifying novel … Read more

Incretin-based diabetes drugs show potential protective effects against dementia

A large McGill University study has found that two classes of medications commonly prescribed for Type 2 diabetes, both incretin-based, are associated with a reduced risk of dementia. Drawing on clinical data from more than 450,000 patients, the research adds to growing evidence that incretin-based therapies have protective benefits for the brain. The study examined GLP-1 … Read more

New framework modernizes traumatic brain injury diagnosis after 50 years

Advanced tools offer improved insights into patients’ condition and their potential for recovery. What’s new: After more than half a century, assessment of traumatic brain injuries gets an overhaul.  Why it matters: Clinicians say the proposed framework will lead to more accurate diagnoses and treatment, providing more rigorous care for some patients and preventing premature discussions about … Read more

Study identifies 17 modifiable risk factors shared between stroke, dementia, and depression

Age-related brain diseases such as stroke, dementia, and late-life depression are a debilitating part of growing older, but people can lower their risk of these diseases through behavioral and lifestyle changes. In a new extensive systematic review, Mass General Brigham researchers identified 17 modifiable risk factors that are shared by stroke, dementia, and late-life depression. … Read more

Study investigates genetic mutations linked to occupational exposures

Occupational and environmental exposures can put specific groups of people at higher risk of cancer, including firefighters. A new study by investigators at Mass General Brigham examines a cancer rarely studied in firefighters: gliomas-a type of tumor that forms in the brain or spinal cord. Using glioma tumor samples from the University of California, San … Read more

Lean and oily fish consumption linked to slower disability progression in MS

A high dietary intake of lean and oily fish may slow the progression of disability in people with multiple sclerosis (MS), suggests a comparative population based study, published online in the Journal of Neurology Neurosurgery & Psychiatry. The anti-inflammatory and neuroprotective properties of the nutrients found in fish may be key, say the researchers, who add … Read more

New review maps the impact of reproductive hormones on neurological health

Archyde The Profound Impact of Reproductive Hormones on Neurological Health Table of Contents 1. The Profound Impact of Reproductive Hormones on Neurological Health 2. Complex Interactions: Hormonal Influence on the Nervous System 3. A Broad Scope of Neurological Conditions 4. Implications for Clinical Practice and Future Research 5. A Tribute to Dr. Seymour Reichlin 6. … Read more