Modified peptides show promise against tuberculosis bacteria

Antibiotic treatments are losing effectiveness against a range of common bacterial pathogens, including E. coli, K. pneumoniae, Salmonella and Acinetobacter, according to a warning issued by the World Health Organization last October. For the microbe that gives rise to tuberculosis, a team of researchers from Penn State and The University of Minnesota Medical School found that a potential solution may be chemically … Read more

Australian researchers develop a new way to target deadly, drug-resistant bacteria

Australian researchers have developed a powerful new way to target deadly, drug-resistant bacteria by designing antibodies that recognize a sugar found only on bacterial cells – an advance that could underpin a new generation of immunotherapies for multidrug resistant hospital-acquired infections. Published in Nature Chemical Biology, the research shows that a laboratory-made antibody can clear … Read more

Breastfeeding habits barely change milk’s microbiome, study reveals

Despite common beliefs, new research shows that how often and how long mothers breastfeed has almost no impact on milk microbiome diversity. Study: The human milk microbiome is minimally associated with breastfeeding practices. Image credit: comzeal images/Shutterstock.com A recent paper in the journal Scientific Reports explored associations between human milk bacteria and breastfeeding attributes. Introduction Breast milk is … Read more

Antimicrobial resistance pattern of Acinetobacter baumannii clinical isolate in Ethiopia. A systematic review and meta-analysis | BMC Infectious Diseases

WHO. Antimicrobial resistance. 2023. https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance. Mancuso G, Midiri A, Gerace E, Biondo C. Bacterial antibiotic resistance: the most critical pathogens. Pathogens. 2021;10(10): 1310. CAS  PubMed  PubMed Central  Google Scholar  Catherine Nonyelum S, Amaka Marian A, Ukamaka Chinelo O. Acinetobacter baumannii: epidemiology, clinical manifestations and associated infections. In: Karyne R, Salvatore Giovanni DS, editors. The rise … Read more

New antibiotic-resistant superbug discovered in Malaysian hospital

A virulent strain of antibiotic-resistant ‘superbug’ that causes severe disease has been found circulating in a Malaysian hospital – posing significant challenges to global public health, a new study reveals.  Analyzing 10 years’ worth of data, scientists discovered that most Acinetobacter baumannii (A. baumannii) infections at the main tertiary hospital in Terengganu, Malaysia, belonged to Global … Read more

Hospital sink drains found to harbor dangerous antibiotic-resistant bacteria

We hope to be cured when we stay in hospital. But too often, we acquire new infections there. Such ‘healthcare-associated infections’ (HAI) are a growing problem worldwide, taking up an estimated 6% of global hospital budgets. In the EU alone, HAIs add up to more than 3.5 million cases per year, resulting in 2.5 million … Read more