Biomedical engineers have developed an artificial intelligence (AI)–enhanced pen for personalized handwriting analysis to aid in the early diagnosis of Parkinson’s disease (PD). In a small pilot study, the “diagnostic pen” accurately recorded handwriting signals, and neural network-assisted analysis successfully distinguished PD from non-PD handwriting with greater than 95% accuracy. “Further validation through large-scale human … Read more
TOPLINE: Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) administered at off-label reduced dosing maintained weight-loss benefits, with patients retaining the effects even with 2-4 weeks between doses. METHODOLOGY: GLP-1 RAs are transforming obesity treatment, but high costs and shortages limit patient access. Clinicians have suggested a less frequent dosing to maintain weight loss, but evidence … Read more
TOPLINE: In 2022, nearly one third of young adults in the United States used electronic nicotine products, and almost one third of the young adults who used them attempted to quit, with social support being the most commonly used cessation method. METHODOLOGY: Researchers performed a secondary analysis and analyzed Wave 7 data, collected between January … Read more
TOPLINE: In patients with chronic vulvar complaints, allergic contact dermatitis (ACD) shows high prevalence with 86.6% exhibiting positive patch test reactions, of which 37.9% were clinically relevant. Nearly half of patients (43.3%) had reactions to spices and herbs, with 34.5% having clinically relevant reactions. METHODOLOGY: Researchers conducted a retrospective analysis of 67 adult patients with … Read more
TOPLINE: Most patients with psoriasis experienced clinical improvement or remission after metabolic and bariatric surgery (MBS) in a systematic review. METHODOLOGY: Researchers conducted a systematic review of 14 studies that included 169 patients (mean age, 46.8 years; 74% women) with psoriasis who underwent MBS. Participants underwent various surgical procedures; gastric bypass was the most common … Read more
TOPLINE: Patients with Sjögren disease (SjD) had a 68% higher risk for overall malignancy than the general population, with hematologic malignancies contributing more to this elevated risk than solid tumors. Cancer accounted for 23.8% of deaths, with older age at diagnosis, smoking, lymphadenopathy, splenomegaly, and cryoglobulinemia identified as key predictors. METHODOLOGY: Researchers conducted a prospective … Read more
TOPLINE: An emergency department (ED)–based alert led to a higher rate of A1c testing among patients with diabetes overdue for routine monitoring but did not significantly improve long-term glycemic control. METHODOLOGY: In this retrospective study, the researchers analyzed 348,490 ED visits by patients with diabetes from January 2017 to September 2023. In November 2017, an … Read more
TOPLINE: Premature infants exposed to multiple courses of antibiotics around the time of birth had weaker lung function and a higher risk for asthma episodes by early school age than those with lower exposure. METHODOLOGY: The study analyzed 3820 premature infants born between 22 and 36 weeks of gestation with low birth weights (< 1500 … Read more
TOPLINE: Zimlovisertib plus tofacitinib showed greater efficacy than tofacitinib alone in reducing Disease Activity Score in 28 joints using C-reactive protein (DAS28-CRP) in patients with rheumatoid arthritis (RA), with a significant reduction observed at week 12. METHODOLOGY: This randomized, phase 2 study, conducted across 77 centers in 10 countries, aimed to evaluate the efficacy, safety, … Read more
Ryan W. Stidham, MD, MS Artificial intelligence (AI) is used in ulcerative colitis to assist in the assessment, monitoring, and management of disease. To explain how this technology is being applied in the clinical setting, Janelle McSwiggin, MSN, RN, spoke with Ryan W. Stidham, MD, MS, associate professor in the Division of Gastroenterology at University … Read more