TOPLINE: Four clinical organizations jointly released a clinical advisory with evidence-based nutrition and lifestyle interventions to enhance glucagon-like peptide 1 (GLP-1) treatment outcomes for obesity. METHODOLOGY: An expert group comprised of multiple clinical and research disciplines assessed the literature to identify pragmatic priorities for nutrition and other lifestyle interventions relevant to GLP-1 treatment for obesity. … Read more
TOPLINE: A recent study found that antiretroviral therapy adherence below 90% was associated with significantly lower odds of viral suppression among women living with HIV. METHODOLOGY: Researchers analyzed data from community-based prospective cohort study including women living with HIV across British Columbia, Ontario, and Quebec between 2013 and 2018. Overall, 1187 participants (median age, 42 … Read more
TOPLINE: An emergency department (ED)–based alert led to a higher rate of A1c testing among patients with diabetes overdue for routine monitoring but did not significantly improve long-term glycemic control. METHODOLOGY: In this retrospective study, the researchers analyzed 348,490 ED visits by patients with diabetes from January 2017 to September 2023. In November 2017, an … Read more
The Evolving Landscape of Colorectal Cancer Screening: Balancing Convenience and Accuracy Table of Contents The Evolving Landscape of Colorectal Cancer Screening: Balancing Convenience and Accuracy The Challenge of Screening Adherence The Appeal of Blood-Based Screening A Closer Look at Performance and Limitations the Importance of Follow-Up and Future Directions The Ongoing Debate: Optimizing Colorectal Cancer … Read more
TOPLINE: In a modeling analysis, initiating direct acting or nonvitamin K oral anticoagulants (DOAC/NOAC) in patients with device-detected subclinical atrial fibrillation (AF) provided a net gain of approximately 1 additional quality-adjusted week of life per patient over 10 years, equating to a 65.8% chance of treatment offering more benefits than withholding it. METHODOLOGY: Previous randomized … Read more
What’s Stalling PrEP’s Success in Europe’s HIV Fight Medscape Source link
Rethinking Antibiotic Duration for Childhood UTIs: A New Approach to Treatment Table of Contents Rethinking Antibiotic Duration for Childhood UTIs: A New Approach to Treatment shorter Antibiotic Courses for kids’ UTIs: New Research & Guidelines The Evolving Landscape of Pediatric UTI Treatment What the Latest Research Shows understanding Uncomplicated UTIs in Children Diagnosing a UTI … Read more
TOPLINE: In children with febrile urinary tract infections (UTIs), individualised antibiotic treatment stopping at 3 days after the achievement of adequate clinical improvement compared with the standard 10-day treatment regimen increased the risk for recurrent infections but reduced antibiotic use and the number of days of adverse events. METHODOLOGY: Researchers conducted a pragmatic trial (INDI-UTI) … Read more
The increasing use of technology for treating type 1 diabetes (T1D) has improved glycemic control; however, it hasn’t eliminated the risk for diabetic ketoacidosis (DKA). In fact, without early recognition, insulin pump malfunctions can directly lead to DKA. Currently, patients test ketones at home using urine test strips that measure acetoacetate (the primary ketone body) … Read more
Even though older adults are more likely to be diagnosed with colorectal cancer (CRC), there is a concerning rise in diagnoses among younger adults, making it essential for healthcare providers to educate adult patients of all ages about the lifestyle-related risk factors associated with the disease. Many are familiar with the modifiable risk factors of … Read more