The immune system must be able to quickly attack invaders like viruses, while also ignoring harmless stimuli, or allergies can result. Immune cells are known to ignore or “tolerate” molecules found on the body’s own healthy cells, for instance, as well as nonthreatening substances from outside the body like food. How the system achieves the … Read more
Tim-3 is an immune checkpoint molecule involved in immunity and inflammation recently linked to late-onset Alzheimer’s disease (AD), but its role in the brain was unknown until now. In a paper published in Nature, researchers from Mass General Brigham used preclinical models to uncover Tim-3’s role in microglia, the brain’s resident immune cells, and have … Read more
Archyde New Kits Enhance Detection of Host Cell Proteins in Biotherapeutics new kits Enhance Detection of Host Cell Proteins in Biotherapeutics Ensuring the safety and efficacy of biotherapeutics requires meticulous attention to detail throughout the progress process. One critical step is the removal of host cell proteins (HCPs), which can trigger immune responses in patients … Read more
Gyros Protein Technologies AB, a pioneer in automated nanoliter-scale immunoassays and leading provider of peptide synthesizers, today announced the introduction of its Gyrolab® HEK293 HCP Type SN Kit Reagents and Gyrolab HEK293 HCP Type CL Kit Reagents. Developed with antibodies from BioGenes GmbH, a global leader in host cell protein (HCP) assay development, the new kits … Read more