Biotherapeutics

Vaginal microbiome may play key role in pregnancy health and preterm birth risk, researchers say

by

Scientists reveal how shifts in the vaginal microbiome during pregnancy may influence inflammation and preterm birth risk, pointing to new microbiome-based therapies that could improve maternal and infant health outcomes. Study: The vaginal microbiome in pregnancy and preterm birth: mechanisms, disparities, and therapeutic opportunities. Image Credit: Kateryna Kon / Shutterstock In a recent review published … Read more

Engineered Listeria boosts innate immunity against cancer

by

After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system to cause listeriosis, Daniel Portnoy and his colleagues have discovered a way to turn the bacteria into a potent booster of the immune system – and a potential weapon against cancer. Three years ago, Portnoy cofounded a … Read more

Discovery of special dendritic cells sheds light on food allergy prevention

by

The immune system must be able to quickly attack invaders like viruses, while also ignoring harmless stimuli, or allergies can result. Immune cells are known to ignore or “tolerate” molecules found on the body’s own healthy cells, for instance, as well as nonthreatening substances from outside the body like food. How the system achieves the … Read more

Tim-3 identified as promising therapeutic target for Alzheimer’s disease

by

Tim-3 is an immune checkpoint molecule involved in immunity and inflammation recently linked to late-onset Alzheimer’s disease (AD), but its role in the brain was unknown until now. In a paper published in Nature, researchers from Mass General Brigham used preclinical models to uncover Tim-3’s role in microglia, the brain’s resident immune cells, and have … Read more

Gyros Protein Technologies Introduces New HEK293 HCP Type SN and CL Kit Reagents

by

Archyde New Kits ‍Enhance Detection of Host Cell Proteins in Biotherapeutics new kits Enhance Detection‍ of ⁣Host Cell Proteins ⁢in Biotherapeutics Ensuring the ⁣safety ​and efficacy of biotherapeutics requires meticulous‌ attention⁢ to detail throughout the progress process. One critical step‌ is the ⁢removal of host cell ⁣proteins⁣ (HCPs), which can⁤ trigger immune​ responses in patients … Read more

Gyros Protein Technologies introduces Gyrolab HEK293 HCP Type SN and Type CL Kit Reagents to support biotherapeutic development

by

Gyros Protein Technologies AB, a pioneer in automated nanoliter-scale immunoassays and leading provider of peptide synthesizers, today announced the introduction of its Gyrolab® HEK293 HCP Type SN Kit Reagents and Gyrolab HEK293 HCP Type CL Kit Reagents. Developed with antibodies from BioGenes GmbH, a global leader in host cell protein (HCP) assay development, the new kits … Read more