A new international study published in The Lancet eClinicalMedicine has mapped global blood transfusion practices for life-threatening abdominal injuries, highlighting significant variation in care worldwide and opportunities for health systems to learn from one another. The research, led by the University of Cambridge as part of the GOAL-Trauma study, analysed data from 1,768 patients treated in … Read more
A new study uncovers how diabetic red blood cells release toxic packages that damage blood vessels, revealing a promising path for preventing serious complications. EVs derived from RBCs of patients with T2D are taken up by the endothelium and impair endothelium-dependent relaxation via an EV-mediated transfer of the prooxidant enzyme Arg1. Proteoglycan remodeling is a … Read more
TOPLINE: National rates of uterine rupture in trial of labor after cesarean (TOLAC) increased from 0.20% in 2010 to 0.37% in 2022, with an annual percentage increase of 6.2%. Among 1,016,073 deliveries analyzed, 2888 uterine ruptures occurred, representing 0.28% of cases. METHODOLOGY: Researchers conducted a repeated cross-sectional analysis using natality files from the National Vital … Read more
Red blood cell transfusions (RBCTs) are life-saving treatments for critically ill patients suffering from anemia, a condition where the body lacks enough healthy red blood cells to deliver oxygen effectively. While effective in increasing oxygen levels in the blood, transfusions can disrupt blood flow and oxygen distribution, potentially causing harm to vital organs like the … Read more