Supplemental imaging techniques could more than triple cancer detection in dense breasts compared with standard care alone, according to new research. The study, published in The Lancet, found that abbreviated magnetic resonance imaging (AB-MRI) and contrast-enhanced mammography (CEM) could help detect an additional 3500 breast cancer cases per year in the UK. Around 2.2 million … Read more
Women who gain a more substantial amount of weight after being diagnosed with breast cancer face an increased risk of dying from the disease, according to findings from a new study. However, that higher mortality risk only appears to apply to women who are overweight or at a healthy weight before diagnosis, not to those who … Read more
As Hurricane Helene approached western North Carolina, Martin Palmeri, MD, MBA, didn’t anticipate the storm would disrupt practice operations for more than a day or so. But the massive rainfall and flooding damage last September proved to be far more challenging. Despite best efforts by the 13-physician practice, basic treatments for most patients were interrupted … Read more
Rates of certain cancers in the United States — including breast, colorectal, and thyroid cancers — increased between 2010 and 2019 among patients aged less than 50 years, while overall cancer incidence and mortality rates did not increase, a new study found. Among the more than two million cases of early-onset cancer diagnosed during this … Read more
TOPLINE: In a multicenter cohort study of 575 South Korean patients with BRCA1 or BRCA2 pathogenic variants, breast-conserving treatment demonstrated comparable oncologic outcomes to mastectomy over a median follow-up of 8.3 years. After propensity score matching, no significant differences between the two surgical approaches were found in terms of locoregional recurrence, distant recurrence, and overall … Read more
TOPLINE: Among women aged 70 years or older with screen-detected breast cancer, those with a history of screening mammography within 5 years of their diagnosis were much more likely to be diagnosed at an earlier stage and much less likely to die from breast cancer, according to a new analysis of over 13,000 women. METHODOLOGY: … Read more
TOPLINE: In patients with metastatic breast cancer (BC), the prevalence of brain metastases increased with each treatment line, rising the most among patients with hormone receptor (HR)–negative, human epidermal growth factor receptor 2 (HER2)–positive disease and the least among those with HR-positive, HER2-negative disease. METHODOLOGY: Brain metastases indicate a poor prognosis in patients with metastatic … Read more
The American Society of Clinical Oncology (ASCO) has released updated guidelines to guide fertility preservation for people with cancer, with the previous update published in 2018. The 2025 update reflects substantial growth in the evidence base, with 166 studies incorporated compared with just 61 studies in the 2018 guidelines. According to the authors, this expanded … Read more
This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Ursula A. Matulonis, MD: Hello. I’m Dr Ursula Matulonis. Welcome to season 2 of the Medscape InDiscussion Endometrial Cancer podcast series. I am honored to have as … Read more
TOPLINE: A review of the distribution of risk estimates from three commonly used genomic assays for breast cancer found that Black women were more likely to have aggressive tumor phenotypes, which contributed to poorer outcomes. Such disparities persisted after adjusting for genomic risk scores and tumor subtypes. While these tests remain valuable for guiding treatment … Read more