Q: How would you summarize your study for a lay audience? Our study investigated the role of astrocytes, an abundant cell type in the brain, in regulating an immune response against glioblastoma (GBM)-a highly aggressive brain cancer. We found a subset of astrocytes that limits the immune response and can be targeted with therapeutics. Q: … Read more
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Iconic singer and two-time Grammy-award winner, Michael Bolton, known for timeless hits like “When a Man Loves a Woman” and “How Am I Supposed to Live Without You?”, recently opened up on his battle with glioblastoma, a rare and aggressive form of brain cancer. Diagnosed in December 2023, the 72-year-old artist has since undergone multiple … Read more
Yale scientists have discovered a promising way to trigger immune responses against certain tumors, using a lupus-related antibody that can slip, undetected, into “cold” tumors and flip on an immune response that has been turned off by cancer. The research, published in Science Signaling on March 25, offers new findings that could help improve therapies … Read more
Diagnostic Imaging’s Weekly Scan: February 16 — February 22 Diagnostic Imaging Source link
Tumor sphericity on preoperative magnetic resonance imaging (MRI) may play a significant role in the prognosis and management of patients with IDH-wildtype glioblastoma (GBM). In a retrospective study, recently published in Insights into Imaging, researchers reviewed preoperative MRI data from 842 patients with IDH-wildtype GBM in order to assess the prognostic impact of tumor sphericity … Read more
Scientists from the German Cancer Research Center (DKFZ) and ShanghaiTech University have developed an innovative method for growing brain tumors of individual patients in the laboratory that mimic the original structure and the molecular property of the parental tumor as closely as possible. Drug tests in this model were found to correlate very well with … Read more