Hepatitis C drug may prevent hepatitis E virus replication

A drug that is already in clinical trials against hepatitis C virus can also prevent hepatitis E virus from replicating. Around 70,000 people die each year from infections with the hepatitis E virus. There is currently neither a vaccine nor a specific drug against this virus. This could change with the identification of bemnifosbuvir as … Read more

Faster hepatitis C treatment with interdisciplinary primary care

Background: Hepatitis C virus treatment is increasingly being offered in primary care because medications now require less frequent monitoring and have fewer adverse effects. However, many primary care clinicians still defer treatment to specialists due to administrative burdens, including laboratory workup, insurance prior authorizations, and pharmacy coordination, which can delay care. The innovation: At an … Read more

Age-period-cohort and bayesian age-period-cohort prediction modeling of hepatitis C incidence and mortality in China | BMC Public Health

Trends in incidence and mortality rates of hepatitis C From 1992 to 2021, China exhibited distinct trends in hepatitis C incidence and mortality, with standardized rates declining significantly but absolute mortality increasing, alongside persistent gender disparities (Figures S1A-1B, and TableĀ 1). The total number of hepatitis C cases decreased by 31.54%, from 1,655,913.50 (95% uncertainty interval … Read more

Researchers to investigate new hepatitis B-like virus and its impact on cats

Photo: Stepan Popov/Adobe Stock With chronic hepatitis potentially being more common in cats than believed, according to a feline virologist at the City University of Hong Kong, a group of researchers and specialists are coming together to study the first hepatitis B-related virus found in carnivores. Specifically, their research will center on how the virus … Read more

Review explores the underlying mechanisms of hepatocarcinogenesis post-HCV eradication

Hepatitis C virus (HCV) infection remains a major global health burden, affecting millions worldwide and contributing significantly to hepatocellular carcinoma (HCC) development. The introduction of direct-acting antivirals (DAAs) has revolutionized HCV treatment, achieving high rates of sustained virologic response (SVR) and reducing HCV-associated morbidity and mortality. Despite these advancements, the risk of HCC persists in … Read more

Global progress, challenges and strategies in eliminating public threat of viral hepatitis | Infectious Diseases of Poverty

In 2024, the WHO updated its guidelines for the prevention, diagnosis, treatment, and care of individuals infected with chronic hepatitis B [5]. The updated guidelines simplify clinical algorithms for the diagnosis, treatment, and monitoring of hepatitis B, expand treatment eligibility criteria, and provide alternative treatment options. The updated guidelines recommend four treatment eligibility options that … Read more