Scientists at the Institute for Basic Science (IBS) have uncovered a non-invasive method to boost the brain’s natural waste drainage system-a discovery that could open new avenues for tackling age-related neurological disorders. In a study published in Nature, researchers from the IBS Center for Vascular Research, led by Director KOH Gou Young, along with senior … Read more
A decade ago, a clinical trial in the U.K. famously showed that children who were exposed to peanuts in the early months of life had reduced risk of developing a peanut allergy compared with children who avoided peanuts. Now, researchers at Memorial Sloan Kettering Cancer Center (MSK) have a likely answer as to why that’s the case: … Read more
TOPLINE: In a multicenter cohort study of 575 South Korean patients with BRCA1 or BRCA2 pathogenic variants, breast-conserving treatment demonstrated comparable oncologic outcomes to mastectomy over a median follow-up of 8.3 years. After propensity score matching, no significant differences between the two surgical approaches were found in terms of locoregional recurrence, distant recurrence, and overall … Read more
TOPLINE: Patients with clinically node-negative breast cancer after neoadjuvant chemotherapy demonstrated low axillary and locoregional recurrence rates after sentinel lymph node biopsy (SLNB) or targeted axillary dissection. METHODOLOGY: More conservative treatment options for women with node-positive breast cancer include SLNB and targeted axillary dissection. However, data comparing patient outcomes after targeted axillary dissection and SLNB … Read more
Bladder cancer is one of the most common malignant tumors in urinary system, and the treatment faces huge challenges. Radical cystectomy (RC) is the primary treatment for invasive cases, yet the prognosis remains grim due to lymph node metastasis. Pelvic lymph node dissection (PLND) plays a vital role in improving survival rates and optimizing treatment … Read more
Research reveals how the dietary flavonoid promotes regulatory T cell development and suppresses inflammation through key immune pathways. Study: Kaempferol Exerts Anti-Inflammatory Effects by Accelerating Treg Development via Aryl Hydrocarbon Receptor-Mediated and PU.1/IRF4-Dependent Transactivation of the Aldh1a2/Raldh2 Gene in Dendritic Cells. Image Credit: Danijela Maksimovic/Shutterstock.com In a recent article published in the Allergy, a group of researchers studied … Read more