How gut imbalance may drive obesity, diabetes, and heart disease

A sweeping new review shows how disruptions in the gut microbiome may fuel obesity, insulin resistance, and cardiovascular risk, while pointing to diet and other microbiome-focused strategies that could help restore metabolic balance. Integrative mechanistic framework linking gut dysbiosis to systemic metabolic dysfunction. Arrows indicate the progression of events from exogenous and host-related factors to … Read more

Wholegrain rye changes gut bacteria and lowers inflammation in obesity trial

A 12-week randomized trial found that wholegrain rye did not beat refined wheat for weight loss, but it did reduce inflammation and shift gut microbiota and short-chain fatty acids in potentially beneficial ways. Key takeaways Rye did not outperform wheat for weight loss Rye reduced inflammation after 12 weeks Rye altered gut bacteria and short-chain … Read more

Specific gut bacteria may signal long-term risk of heart and metabolic disease

A large prospective study links specific gut microbes and diet-derived metabolites to future cardiometabolic disease risk, highlighting how the microbiome may reflect lifestyle factors shaping long-term heart health. Study: Specific gut microbes are associated with the incidence of cardiometabolic disease in the HELIUS cohort. Image Credit: Anusorn Nakdee / Shutterstock In a recent study published … Read more

Researchers propose that Parkinson’s disease may start in the gut, not the brain

Scientists propose that Parkinson’s disease may begin far from the brain, where environmental toxins, microbiome disruption, and intestinal barrier damage interact to ignite the biological cascade leading to neurodegeneration. Environmental insults reduce gut resilience and initiate convergent mechanisms that drive Parkinson’s disease. A lifetime of environmental insults (including Western diets and food additives, nano- and microplastics, … Read more

Dietary fat ratios impact the strength of immune cells and ability to fight disease

The types of fats we consume directly impacts the survival and strength of the body’s immune cells and ability to fight disease, researchers have found. A University of Queensland team led an international collaboration that found diet could change the fat composition inside T cells – the immune cells that help protect a person from … Read more

Colorful japonica rice varieties show unique health-promoting lipids

Rice feeds more than half of the world’s population, yet we still only partly understand the nutrients it contains. More than 85% of the rice we eat is composed of starch, though it also contains some protein (around 10%), small amounts of fat (roughly 2%), a few vitamins, and trace elements. Because fats, or lipids, … Read more

Engineered liver tissue model mimics early metabolic liver disease

More than 100 million people in the United States suffer from metabolic dysfunction-associated steatotic liver disease (MASLD), characterized by a buildup of fat in the liver. This condition can lead to the development of more severe liver disease that causes inflammation and fibrosis. In hopes of discovering new treatments for these liver diseases, MIT engineers … Read more

Blood protein albumin identified as key defense against deadly black fungus

A new international study published in Nature has identified albumin, the most abundant protein in human blood, as a powerful and previously unrecognized defense against mucormycosis, a rare but often fatal fungal infection. The research was led by George Chamilos, MD and his laboratory at the University of Crete and Institute of Molecular Biology and Biotechnology, with critical contributions from a Lundquist Institute for Biomedical … Read more

Algae may help meet future protein demand without straining the planet

From high-quality protein to omega-3s and antioxidants, algae emerge as a promising but carefully qualified solution for future nutrition and sustainability challenges. Spirulina sp. blue-green algae under microscopic view x100. Image Credit: Elif Bayraktar / Shutterstock. Study: Algae and Algal Protein in Human Nutrition: A Narrative Review of Health Outcomes from Clinical Studies In a … Read more

Can dietary supplements support nutrition security as climate change disrupts food systems?

As climate stressors disrupt food systems and nutrient quality worldwide, researchers examine whether dietary supplements could support resilience and nutrition security or whether their role remains unproven amid major evidence and policy gaps. Perspective: The Role of Dietary Supplements in Environmental Challenges. Image Credit: Artem Stepanov / Shutterstock In a recent scholarly perspective piece published … Read more