Personalized exercise and coaching could improve health of people with neuromuscular diseases

While many people with neuromuscular diseases currently face a future without a cure, a new study finds that a personalized exercise and coaching program could improve their fitness and overall health. The study is published on June 4, 2025, online in Neurology®, the medical journal of the American Academy of Neurology. The study looked at … Read more

Epileptic seizures more common in frontotemporal dementia patients than previously known

According to a recent study, in patients with frontotemporal dementia (FTD), epileptic seizures are significantly more common than previously known. The discovery deepens understanding of the symptoms of this memory disorder and emphasises the importance of taking epileptic seizures into account in the treatment and monitoring of patients.  Coordinated by Neurocenter Finland, this major project … Read more

Examining Tominersen as a Potential Treatment for Huntington Disease: The GENERATION HD2 trial

Huntington disease (HD) is a rare, inherited neurological condition that progressively impacts movement, cognitive abilities, and behavior. Early signs can include subtle changes in mood, thinking, and behavior, which may not immediately interfere with daily functioning. As the disease advances, individuals may experience involuntary, jerky movements that interfere with basic tasks such as walking and … Read more

What’s Coming for Huntington’s Disease

Huntington’s disease (HD) is a progressive, inherited neurodegenerative disorder marked by movement abnormalities, cognitive decline, and psychiatric symptoms. Caused by a CAG repeat expansion in the HTT gene, the resulting toxic buildup of mutant huntingtin protein leads to widespread neuronal damage. Despite advances in genetic testing and diagnosis, there are still no disease-modifying therapies—only symptomatic … Read more

Men with common genetic variant twice as likely to develop dementia

New research has found that men who carry a common genetic variant are twice as likely to develop dementia in their lifetime compared to women. The research, published in Neurology, used data from the ASPirin in Reducing Events in the Elderly (ASPREE) trial to investigate whether people who had variants in the haemochromatosis (HFE) gene, … Read more

Research uncovers new links between blood lipid profiles and risk of developing Alzheimer’s

People who are at higher risk for heart disease also seem more likely to develop dementia. And research led by The University of Texas Health Science Center at San Antonio (UT Health San Antonio) has discovered new associations between various lipid, or fat, levels in the blood and the risk of developing Alzheimer’s disease, the … Read more

SSRIs Restore Brain Function in Alzheimer’s

Summary: A new study suggests that SSRIs, commonly prescribed antidepressants, may reduce biological markers of Alzheimer’s disease. In a cohort of 191 individuals, AD patients on SSRIs had lower levels of plasma phosphorylated tau-181, a key indicator of disease severity. Brain scans also showed that SSRIs restored metabolic activity in the dorsal raphe nucleus (DRN), … Read more

Dementia Risk: Gene Variant Affects Men Differently

BREAKING: Gene Variant Doubles Dementia Risk in Men BREAKING: Gene variant Doubles Dementia Risk in Men By Anya Sharma | SYDNEY – 2025/05/30 22:16:57 A new study reveals… The post Dementia Risk: Gene Variant Affects Men Differently appeared first on NewsyList. Source link

Elisabeth Sonesson, PhD, on Imlifidase’s Targeted, Fast-Acting Approach to GBS

At the 2025 Peripheral Nerve Society (PNS) Annual Meeting, held May 17-20, in Edinburgh, Scotland, investigators from Hansa Biopharma presented data from a phase 2, open-label study (NCT03943589) testing investigational imlifidase, an IgG-cleaving antibody, in patients with Guillain-Barré syndrome (GBS). After excluding those re-diagnosed with other conditions, the study featured 27 patients with confirmed severe … Read more

Dementia Diagnoses Decline, But More Are Living Longer With the Disease

Summary: A new study of over 25 million Medicare recipients found that while dementia incidence in the U.S. is declining, more older adults are living longer with the condition. From 2015 to 2021, new diagnoses dropped from 3.5% to 2.8%, yet prevalence increased to nearly 12%. The findings underscore a growing need for long-term care … Read more