A new system that uses artificial intelligence (AI) to assess cardiovascular risk based on images of the eye captured during eye exams demonstrated strong correlation with a standard cardiovascular risk assessment, according to a study presented at the American College of Cardiology’s Annual Scientific Session (ACC.26). Researchers said using AI to screen for heart disease … Read more
Despite experiencing significant reductions in triglycerides, patients with triglycerides over 150 mg/dL and a high risk of atherosclerosis did not experience any significant change in the amount of non-calcified plaque in their coronary arteries after taking the triglyceride-lowering drug olezarsen, in a one-year sub-study presented at the American College of Cardiology’s Annual Scientific Session (ACC.26). … Read more
A large prospective study links specific gut microbes and diet-derived metabolites to future cardiometabolic disease risk, highlighting how the microbiome may reflect lifestyle factors shaping long-term heart health. Study: Specific gut microbes are associated with the incidence of cardiometabolic disease in the HELIUS cohort. Image Credit: Anusorn Nakdee / Shutterstock In a recent study published … Read more
Jebari-Benslaiman, S. et al. Pathophysiology of Atherosclerosis. Int. J. Mol. Sci. 23 https://doi.org/10.3390/ijms23063346 (2022). Bergstrom, G. et al. Prevalence of subclinical coronary Artery atherosclerosis in the general population. Circulation 144, 916–929. https://doi.org/10.1161/CIRCULATIONAHA.121.055340 (2021). Google Scholar Lind, L. et al. Obesity is associated with coronary artery stenosis independently of metabolic risk factors: The population-based SCAPIS study. … Read more
Atherosclerosis underlies most heart attacks and strokes and is now recognized as a chronic inflammatory disease rather than a simple disorder of cholesterol deposition. While immune cells such as macrophages have been widely studied, emerging evidence shows that vascular smooth muscle cells also play a central role in plaque development. These cells exhibit remarkable plasticity, … Read more
A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae-responsible for atypical pneumonia and other respiratory infections-to obtain cholesterol and other essential lipids directly from the human body. The discovery, published in Nature Communications, was co-led by Dr. Noemà Rotllan, from the Sant Pau Research Institute (IR Sant Pau) and … Read more
A newly published randomized controlled trial in Frontiers in Medicine has found that the practice of Transcendental Meditation® (TM) may significantly reduce the risk of major adverse cardiovascular events (MACE) in Black men and women at high risk for heart disease. The study compared TM with a standard health education (HE) program and found a 65% … Read more
Lipid-lowering medicines, known as statins, are prescribed in cases of high cholesterol levels, to reduce the risk of atherosclerosis, heart attack and stroke. The results of some small studies suggest that statins could also have an antidepressive effect. Researchers from Charité – Universitätsmedizin Berlin have now conducted an extensive study to investigate this claim. However, they could … Read more
People who are at higher risk for heart disease also seem more likely to develop dementia. And research led by The University of Texas Health Science Center at San Antonio (UT Health San Antonio) has discovered new associations between various lipid, or fat, levels in the blood and the risk of developing Alzheimer’s disease, the … Read more
 Cardiovascular diseases (CVDs) continue to dominate global mortality statistics, with immune dysregulation emerging as a central feature in their pathogenesis. This review by Gareev et al. focuses on immune-derived microRNAs (immuno-miRs) as pivotal modulators of immune responses in cardiovascular settings, highlighting their roles in pathophysiology, diagnostic potential, and therapeutic promise. Introduction … Read more