Research suggests new therapeutic targets for broad-spectrum antiviral drugs

Coronaviruses not only use the machinery of the human cells they infect: they modify it to achieve optimal conditions to produce viral proteins and thus spread more quickly. This is the main conclusion of a study by Pompeu Fabra University published in Nature Communications. The study identifies enzymes that modify transfer RNAs (tRNAs) –small cellular … Read more

Tumor-targeted chimeric drug increases efficacy and limits side effects

Wistar scientists have combined a promising cancer therapy with a molecule that targets tumors to treat cancer more effectively. The new approach could be a way to deliver treatment directly to tumors at higher doses, while reducing side effects in healthy tissue. An Aurora kinase A (AURKA) inhibitor is viewed as a lethal synthetic … Read more