Infectious disease can afflict a population in complex ways. Understanding the varying risks is an equally complex challenge. The Centers for Disease Control and Prevention (CDC) offers a general metric for assessing the risk of natural disasters in a region in terms of Social Vulnerability Index (SVI), which includes socioeconomic and cultural factors that impact … Read more
Alzheimer’s disease affects an estimated 7.2 million Americans age 65 and older, according to the Alzheimer’s Association. Current tests often measure the levels of two proteins-amyloid beta (Aβ) and phosphorylated tau (p-tau)-in the blood or spinal fluid, but these markers may not fully capture earlier biological changes linked to disease progression. Now, scientists at Scripps … Read more
Increasing our level of physical fitness leads to a bigger release of brain-boosting proteins following one session of exercise, a new study led by a UCL researcher has found. The study, published in Brain Research, took a group of inactive unfit participants through a 12-week training programme of cycling three times per week and made … Read more
The prevalence of congenital heart disease points to the need for a better understanding of how it influences neurodevelopment. New in JNeurosci, Jung-Hoon Kim and Catherine Limperopoulos, from Children’s National Hospital, led a study examining brain network disruptions that may be linked to congenital heart disease. Compared to publicly accessible brain imaging data from healthy newborns, babies with … Read more
A single session of physical exercise can spawn a boost of neural activity in brain networks that underlie learning and memory, according to a new study led by the University of Iowa. The researchers measured neural activity in the brains of patients with epilepsy before and after they completed a bout of physical exercise. The … Read more
Background Intracerebral hemorrhage (ICH) is the stroke subtype with the highest mortality and disability rates, and early hematoma evacuation is crucial for improving prognosis. Compared to traditional craniotomy, which involves significant trauma and slow recovery, minimally invasive surgery (MIS) has emerged as a highly promising treatment option due to its advantages of shorter operative time, … Read more
Chimeric antigen receptor T (CAR T) cell therapy represents a milestone in leukemia treatment. CAR T works by genetically engineering a chimeric antigen receptor on the surface of the patient’s T cells to target specific antigens on leukemia cells, with the goal of identifying and eliminating them. However, clinical data show that more than 50% … Read more
People living with neurological diseases such as Parkinson’s disease, dementia and epilepsy face not only physical decline, but also profound questions about identity, purpose, and meaning. Yet physicians best positioned to address those concerns do not have the adequate training and tools to do so, a new paper states. The paper, published in the journal … Read more
For years, a protein inside our cells has quietly powered billions of dollars’ worth of cancer drugs. Now a team of researchers have discovered that this workhorse protein, called cereblon, in addition to its known functions, can also fine‑tune which proteins live and which are sent to the cellular trash. The new study, published in … Read more
Natural light may play a meaningful role in preventing and managing Type 2 diabetes, according to findings from a study presented at the European Association for the Study of Diabetes. The trial tested the impact of different lighting conditions on metabolism in older adults with the condition. In a controlled setting, researchers exposed participants to … Read more