Research

New biotech partnership aims to accelerate stem cell therapies for heart disease

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A new biotech company forged through an Australian and Danish partnership will accelerate treatments for children and adults with heart disease. Harnessing cellular therapies, the company aims to conduct human clinical trials within three to five years. Ibnova Therapeutics, launched today, has emerged from world-first, collaborative research by Murdoch Children’s Research Institute (MCRI) in Melbourne and … Read more

Immune cells found to actively promote plaque formation in Alzheimer’s disease

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A new study led by researchers from VIB and KU Leuven shows that immune cells called microglia can actively promote the formation of plaques in Alzheimer’s disease, challenging the long-standing view that these cells serve only as defenders against plaque buildup. The findings were recently published in PNAS. “Most studies suggest that microglia are there … Read more

Mapping the evolution of AI in organelle segmentation

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In organelle imaging, segmentation aims to accurately delineate pixels or voxels corresponding to target organelles from background, noise, and other cellular structures in microscopy images, thereby generating masks suitable for quantitative analysis. Robust segmentation is foundational to downstream quantification, including morphological characterization, spatial distribution analysis, temporal trajectory tracking, and the detection of key biological events. … Read more

The new 5-minute screening tool for endometriosis detection

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A simple 5-minute test addressing major endometriosis diagnostic delays and treatment has been developed by University of Queensland researchers. The Simplified Adolescent Factors for Endometriosis (SAFE) score uses a questionnaire to identify at-risk patients and fast track specialist referrals for further investigation. Professor Gita Mishra AO, Centre Director of UQ’s Australian Women and Girls’ Health … Read more

“Bugs Delivering Drugs” – Researchers Publish New Approach To Colorectal Cancer Treatment Using Common Food-Borne Bacteria

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Baylor University researchers have published a novel approach to fight colorectal cancer, using modified bacteria as a courier to deliver potent cancer-killing proteins into tumor cells. Michael S. VanNieuwenhze, PhD, FRSC, University Distinguished Professor and chair of the Department of Biology, along with Baylor doctoral students and a colleague at Texas Tech University Health Sciences … Read more

Specific gut bacteria may signal long-term risk of heart and metabolic disease

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A large prospective study links specific gut microbes and diet-derived metabolites to future cardiometabolic disease risk, highlighting how the microbiome may reflect lifestyle factors shaping long-term heart health. Study: Specific gut microbes are associated with the incidence of cardiometabolic disease in the HELIUS cohort. Image Credit: Anusorn Nakdee / Shutterstock In a recent study published … Read more

Sleep and diet emerge as key drivers of immunome variation

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Immunome (immune cells and functions) variations are closely related to human health. Various exposures, including the external environment and personal lifestyles, are important factors affecting the immune system. Recent advances in research have focused on immune system variation mainly from a genome perspective. This population-based study (N=1,001 from The Human Phenome Atlas (THPA) cohort) investigated … Read more

EVA1A regulates fatty acid transporter CD36 in fatty liver disease

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Metabolic Dysfunction-Associated Steatotic Liver Disease（MASLD） is characterized by excessive accumulation of lipids in hepatocytes and is closely associated with the rapid rise in insulin resistance, obesity, and diabetes prevalence, making it one of the most common chronic liver diseases worldwide. Fatty liver can lead to systemic metabolic dysfunction and further progress to steatohepatitis, hepatic fibrosis, … Read more

Hormonal imbalance and gut microbes linked to cognitive deficits in patients with PitNETs

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Pituitary neuroendocrine tumors (PitNETs) are commonly associated with visual disturbances and endocrine abnormalities; however, many patients also experience cognitive deficits, particularly in memory, attention, and executive function, which significantly affect quality of life. Despite increasing recognition of this burden, the mechanisms underlying cognitive impairment remain unclear. Traditionally, cognitive changes have been attributed to tumor mass … Read more